Tick salivary kunitz-type inhibitors: targeting host hemostasis and immunity to mediate successful blood feeding
Kunitz domain-containing proteins are ubiquitous serine protease inhibitors with promising
therapeutic potential. They target key proteases involved in major cellular processes such as …
therapeutic potential. They target key proteases involved in major cellular processes such as …
Small protease inhibitors in tick saliva and salivary glands and their role in tick-host-pathogen interactions
LA Martins, J Kotál, C Bensaoud, J Chmelař… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Ticks must durably suppress vertebrate host responses (hemostasis, inflammation,
immunity) to avoid rejection and act as vectors of many pathogenic microorganisms that …
immunity) to avoid rejection and act as vectors of many pathogenic microorganisms that …
Sialotranscriptomics of the argasid tick Ornithodoros moubata along the trophogonic cycle
The argasid tick Ornithodoros moubata is the main vector of human relapsing fever (HRF)
and African swine fever (ASF) in Africa. Salivary proteins are part of the host-tick interface …
and African swine fever (ASF) in Africa. Salivary proteins are part of the host-tick interface …
RNA-seq analysis and gene expression dynamics in the salivary glands of the argasid tick Ornithodoros erraticus along the trophogonic cycle
R Pérez-Sánchez, Á Carnero-Morán, B Soriano… - Parasites & …, 2021 - Springer
Abstract Background The argasid tick Ornithodoros erraticus is the main vector of tick-borne
human relapsing fever (TBRF) and African swine fever (ASF) in the Mediterranean Basin …
human relapsing fever (TBRF) and African swine fever (ASF) in the Mediterranean Basin …
[HTML][HTML] A multi-omics approach for understanding blood digestion dynamics in Ixodes scapularis and identification of anti-tick vaccine targets
Ixodes scapularis, the black-legged tick, is a major arthropod vector that transmits the
causative agents of Lyme disease and several other pathogens of human significance. The …
causative agents of Lyme disease and several other pathogens of human significance. The …
Proteomics informed by transcriptomics for a qualitative and quantitative analysis of the sialoproteome of adult Ornithodoros moubata ticks
A Oleaga, A Carnero-Morán, ML Valero… - Parasites & …, 2021 - Springer
Abstract Background The argasid tick Ornithodoros moubata is the main vector in mainland
Africa of African swine fever virus and the spirochete Borrelia duttoni, which causes human …
Africa of African swine fever virus and the spirochete Borrelia duttoni, which causes human …
Quantitative visions of reality at the tick-host interface: biochemistry, genomics, proteomics, and transcriptomics as measures of complete inventories of the tick …
BJ Mans - Frontiers in Cellular and Infection Microbiology, 2020 - frontiersin.org
Species have definitive genomes. Even so, the transcriptional and translational products of
the genome are dynamic and subject to change over time. This is especially true for the …
the genome are dynamic and subject to change over time. This is especially true for the …
A proteomics informed by transcriptomics insight into the proteome of Ornithodoros erraticus adult tick saliva
R Pérez-Sánchez, A Carnero-Morán, M Luz Valero… - Parasites & vectors, 2022 - Springer
Abstract Background The argasid tick Ornithodoros erraticus is the main vector of tick-borne
human relapsing fever (TBRF) and African swine fever (ASF) in the Mediterranean Basin …
human relapsing fever (TBRF) and African swine fever (ASF) in the Mediterranean Basin …
Catalogue of stage-specific transcripts in Ixodes ricinus and their potential functions during the tick life-cycle
Background The castor bean tick Ixodes ricinus is an important vector of several clinically
important diseases, whose prevalence increases with accelerating global climate changes …
important diseases, whose prevalence increases with accelerating global climate changes …
Gut membrane proteins as candidate antigens for immunization of mice against the tick Amblyomma sculptum
GCA Costa, ICT Ribeiro, RC Giunchetti, NF Gontijo… - Vaccine, 2024 - Elsevier
Amblyomma sculptum is widely distributed in Brazil and is the main vector of Rickettsia
rickettsii, the causative agent of the Brazilian spotted fever (BSF). Tick gut proteins play an …
rickettsii, the causative agent of the Brazilian spotted fever (BSF). Tick gut proteins play an …