mRNA vaccines for infectious diseases: principles, delivery and clinical translation

N Chaudhary, D Weissman… - Nature reviews Drug …, 2021 - nature.com
Over the past several decades, messenger RNA (mRNA) vaccines have progressed from a
scepticism-inducing idea to clinical reality. In 2020, the COVID-19 pandemic catalysed the …

A comprehensive review of mRNA vaccines

V Gote, PK Bolla, N Kommineni, A Butreddy… - International journal of …, 2023 - mdpi.com
mRNA vaccines have been demonstrated as a powerful alternative to traditional
conventional vaccines because of their high potency, safety and efficacy, capacity for rapid …

Clinical characteristics and outcomes of pregnant women with COVID‐19 and comparison with control patients: A systematic review and meta‐analysis

M Jafari, A Pormohammad… - Reviews in medical …, 2021 - Wiley Online Library
In a large‐scale study, 128176 non‐pregnant patients (228 studies) and 10000 pregnant
patients (121 studies) confirmed COVID‐19 cases included in this Meta‐Analysis. The mean …

Lessons learned 1 year after SARS-CoV-2 emergence leading to COVID-19 pandemic

KKW To, S Sridhar, KHY Chiu, DLL Hung… - Emerging microbes & …, 2021 - Taylor & Francis
Without modern medical management and vaccines, the severity of the Coronavirus
Disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome (SARS) …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): a systemic infection

A Synowiec, A Szczepański… - Clinical microbiology …, 2021 - Am Soc Microbiol
To date, seven identified coronaviruses (CoVs) have been found to infect humans; of these,
three highly pathogenic variants have emerged in the 21st century. The newest member of …

Chronic histiocytic intervillositis with trophoblast necrosis is a risk factor associated with placental infection from coronavirus disease 2019 (COVID-19) and intrauterine …

DA Schwartz, M Baldewijns… - … of pathology & …, 2021 - meridian.allenpress.com
Context.—The number of neonates with severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) infection is increasing, and in a few there are reports of intrauterine infection …

Defining severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) placentitis: a report of 7 cases with confirmatory in situ hybridization, distinct …

JC Watkins, VF Torous… - Archives of pathology & …, 2021 - meridian.allenpress.com
Context.—Case reports and rare case series have demonstrated variable placental
pathology in the setting of maternal severe acute respiratory syndrome coronavirus 2 (SARS …

SARS-CoV-2 B. 1.1. 7 (alpha) and B. 1.351 (beta) variants induce pathogenic patterns in K18-hACE2 transgenic mice distinct from early strains

P Radvak, HJ Kwon, M Kosikova… - Nature …, 2021 - nature.com
SARS-CoV-2 variants of concern (VOC) B. 1.1. 7 (alpha) and B. 1.351 (beta) show increased
transmissibility and enhanced antibody neutralization resistance. Here we demonstrate in …

COVID‐19: immunopathology, pathophysiological mechanisms, and treatment options

LE van Eijk, M Binkhorst, AR Bourgonje… - The Journal of …, 2021 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2), continues to spread globally despite the worldwide …

A placental model of SARS-CoV-2 infection reveals ACE2-dependent susceptibility and differentiation impairment in syncytiotrophoblasts

J Chen, JA Neil, JP Tan, R Rudraraju, M Mohenska… - Nature Cell …, 2023 - nature.com
SARS-CoV-2 infection causes COVID-19. Several clinical reports have linked COVID-19
during pregnancy to negative birth outcomes and placentitis. However, the …