Non-canonical DNA structures: Diversity and disease association
A complete understanding of DNA double-helical structure discovered by James Watson
and Francis Crick in 1953, unveil the importance and significance of DNA. For the last seven …
and Francis Crick in 1953, unveil the importance and significance of DNA. For the last seven …
[HTML][HTML] A bouquet of DNA structures: Emerging diversity
Structural polymorphism of DNA has constantly been evolving from the time of illustration of
the double helical model of DNA by Watson and Crick. A variety of non-canonical DNA …
the double helical model of DNA by Watson and Crick. A variety of non-canonical DNA …
Structurally diverse G-quadruplexes as the noncanonical nucleic acid drug target for live cell imaging and antibacterial study
BX Zheng, J Yu, W Long, KH Chan… - Chemical …, 2023 - pubs.rsc.org
The formation of G-quadruplex structures (G4s) in vitro from guanine (G)-rich nucleic acid
sequences of DNA and RNA stabilized with monovalent cations, typically K+ and Na+, under …
sequences of DNA and RNA stabilized with monovalent cations, typically K+ and Na+, under …
Oxidative stress: role and response of short guanine tracts at genomic locations
Over the decades, oxidative stress has emerged as a major concern to biological
researchers. It is involved in the pathogenesis of various lifestyle-related diseases such as …
researchers. It is involved in the pathogenesis of various lifestyle-related diseases such as …
Unraveling the sequence-dependent polymorphic behavior of d (CpG) steps in B-DNA
PD Dans, I Faustino, F Battistini… - Nucleic acids …, 2014 - academic.oup.com
We have made a detailed study of one of the most surprising sources of polymorphism in B-
DNA: the high twist/low twist (HT/LT) conformational change in the d (CpG) base pair step …
DNA: the high twist/low twist (HT/LT) conformational change in the d (CpG) base pair step …
Specific Binding of Anionic Porphyrin and Phthalocyanine to the G-Quadruplex with a Variety of in Vitro and in Vivo Applications
H Yaku, T Murashima, D Miyoshi, N Sugimoto - Molecules, 2012 - mdpi.com
The G-quadruplex, a four-stranded DNA structure with stacked guanine tetrads (G-quartets),
has recently been attracting attention because of its critical roles in vitro and in vivo. In …
has recently been attracting attention because of its critical roles in vitro and in vivo. In …
Interface of G-quadruplex with both stabilizing and destabilizing ligands for targeting various diseases
S Chaudhary, M Kumar, M Kaushik - International Journal of Biological …, 2022 - Elsevier
Guanine-rich DNA sequences may fold back into non-canonical four-stranded secondary
structures termed as G-quadruplexes. The role of G-quadruplexes has already been well …
structures termed as G-quadruplexes. The role of G-quadruplexes has already been well …
Chemical Biology of Double Helical and Non-Double Helical Nucleic Acids: “To B or Not To B, That Is the Question”
N Sugimoto, T Endoh, S Takahashi… - Bulletin of the …, 2021 - academic.oup.com
Nucleic acids form not only the canonical double helix (duplex) but also the non-canonical
(non-double helix) structures such as triplexes, G-quadruplexes, and i-motifs. The formation …
(non-double helix) structures such as triplexes, G-quadruplexes, and i-motifs. The formation …
Binding of G-quadruplexes to the N-terminal recognition domain of the RNA helicase associated with AU-rich element (RHAU)
Polynucleotides containing consecutive tracts of guanines can adopt an intramolecular G-
quadruplex structure where multiple planar tetrads of hydrogen-bound guanines stack on …
quadruplex structure where multiple planar tetrads of hydrogen-bound guanines stack on …
G-quadruplex prediction in E. coli genome reveals a conserved putative G-quadruplex-Hairpin-Duplex switch
Many studies show that short non-coding sequences are widely conserved among
regulatory elements. More and more conserved sequences are being discovered since the …
regulatory elements. More and more conserved sequences are being discovered since the …