Recent advances in pH/enzyme-responsive polysaccharide-small-molecule drug conjugates as nanotherapeutics
Now-a-days, the polysaccharides are extensively employed for the delivery of small-
molecule drugs ascribed to their excellent biocompatibility, biodegradability and …
molecule drugs ascribed to their excellent biocompatibility, biodegradability and …
Stimuli responsiveness of recent biomacromolecular systems (concept to market): A review
Stimuli responsive delivery systems, also known as smart/intelligent drug delivery systems,
are specialized delivery vehicles designed to provide spatiotemporal control over drug …
are specialized delivery vehicles designed to provide spatiotemporal control over drug …
rs-TAC PDC, a peptide drug-conjugate, for targeted delivery of tacrolimus and sericin alleviates podocyte injury in diabetic nephropathy
S Gao, Y Li, T Zhu, Z Guo, Y Hu, Y Wang, B Lv, A Duan… - Nano Today, 2024 - Elsevier
Despite intensive glucose control or blood pressure control, the remission of proteinuria in
patients with diabetic nephropathy remains extremely low. Tacrolimus has been successful …
patients with diabetic nephropathy remains extremely low. Tacrolimus has been successful …
Amphiphilic Poly (ethylene glycol)-Cholesterol Conjugate: Stable Micellar Formulation for Efficient Loading and Effective Intracellular Delivery of Curcumin
A biodegradable and biocompatible micellar-based drug delivery system was developed
using amphiphilic methoxy-poly (ethylene glycol)-cholesterol (C1) and poly (ethylene glycol) …
using amphiphilic methoxy-poly (ethylene glycol)-cholesterol (C1) and poly (ethylene glycol) …
RGD-HSA-TAC nanoparticles targeted delivery of tacrolimus and attenuation of podocyte injury in diabetic kidney disease
Z Guo, S Gao, F Xu, Z Chen, Q Wang, Z Liu… - Journal of …, 2025 - Springer
Background Diabetic kidney disease (DKD) is a prevalent and severe complication of
diabetes and plays a pivotal role in the pathogenesis and progression of DKD. However, the …
diabetes and plays a pivotal role in the pathogenesis and progression of DKD. However, the …
Sulfated hyaluronic acid gel for the treatment of rheumatoid arthritis in rats
Y Yue, FL Shi, J Wang, Q Ning, Z Zhang, H Lv - International Journal of …, 2024 - Elsevier
Rheumatoid arthritis (RA) is a chronic autoimmune disease. NSAIDS, cyclophosphamide
and glucocorticoid were commonly used to treat RA in clinical application, which long-term …
and glucocorticoid were commonly used to treat RA in clinical application, which long-term …
[引用][C] Novel Semisynthetic Derivative of Dehydrozingerone (DHZ-15) Modulating Lipopolysaccharide Stimulated Macrophages through Targeting NF-kB/p65 …
I Qasam, S Nawaz, N Chauhan - 2024