Functional thermoresponsive hydrogel molecule to material design for biomedical applications

S Pardeshi, F Damiri, M Zehravi, R Joshi, H Kapare… - Polymers, 2022 - mdpi.com
Temperature-induced, rapid changes in the viscosity and reproducible 3-D structure
formation makes thermos-sensitive hydrogels an ideal delivery system to act as a cell …

Recent advances in PLGA based nanocarriers for drug delivery system: a state of the art review

SR Pardeshi, A Nikam, P Chandak… - … Journal of Polymeric …, 2023 - Taylor & Francis
The biomolecules in the clinical use being delivered by the conventional mode of delivery
often exhibit poor affinity. So, there is a need for a nanomedicine-based approach that could …

Green synthesis of antibacterial and cytotoxic silver nanoparticles by Piper nigrum seed extract and development of antibacterial silver based chitosan nanocomposite

P Kanniah, P Chelliah, JR Thangapandi… - International Journal of …, 2021 - Elsevier
In the present study, we have used seed extract of P. nigrum as an effective reducing agent
for the synthesis of silver nanoparticles (Ag NPs) and silver based chitosan nanocomposite …

Design and development of neomycin sulfate gel loaded with solid lipid nanoparticles for buccal mucosal wound healing

KM Hosny, NR Naveen, M Kurakula, AM Sindi… - Gels, 2022 - mdpi.com
Drug administration to the wound site is a potential method for wound healing. The drug
retention duration should be extended, and drug permeability through the buccal mucosal …

QbD supported optimization of the alginate-chitosan nanoparticles of simvastatin in enhancing the anti-proliferative activity against tongue carcinoma

WY Rizg, NR Naveen, M Kurakula, HA Bukhary… - Gels, 2022 - mdpi.com
The goal of the current study is to develop a chitosan alginate nanoparticle system
encapsulating the model drug, simvastatin (SIM-CA-NP) using a novel polyelectrolytic …

Response surface methodology (RSM) powered formulation development, optimization and evaluation of thiolated based mucoadhesive nanocrystals for local …

RB Bakhaidar, NR Naveen, P Basim, SS Murshid… - Polymers, 2022 - mdpi.com
In oral administration systems, mucoadhesive polymers are crucial for drug localization and
target-specific activities. The current work focuses on the application of thiolated xanthan …

Development of nanocrystal compressed minitablets for chronotherapeutic drug delivery

N Sreeharsha, NR Naveen, P Anitha, PS Goudanavar… - Pharmaceuticals, 2022 - mdpi.com
The present work aimed to develop a chronotherapeutic system of valsartan (VS) using
nanocrystal formulation to improve dissolution. VS nanocrystals (VS-NC) were fabricated …

Novel chitosan-silica hybrid hydrogels for cell encapsulation and drug delivery

SN Jayash, PR Cooper, RM Shelton… - International journal of …, 2021 - mdpi.com
Hydrogels constructed from naturally derived polymers provide an aqueous environment
that encourages cell growth, however, mechanical properties are poor and degradation can …

QbD assisted formulation design and optimization of thiol pectin based Polyethyleneglycol and Montmorillonite (PEG/MMT) nanocomposite films of neomycin sulphate …

NR Naveen, P Anitha, B Gowthami… - Journal of Drug Delivery …, 2023 - Elsevier
Skin wound healing, especially for chronic sores like diabetic foot ulcers, is still a medical
emergency. Despite the abundance of treatment techniques that are currently accessible …

Recent progress in thermosensitive hydrogels and their applications in drug delivery area

B Khan, A Arbab, S Khan, H Fatima… - MedComm …, 2023 - Wiley Online Library
The scientific community has widely recognized thermosensitive hydrogels as highly
biocompatible material with immense potential in drug delivery systems. When the …