Microtubule dynamics and their control are essential for the normal function and division of
all eukaryotic cells. This plethora of functions is, in large part, supported by dynamic …

▪ Abstract Microtubules are polymers that are essential for, among other functions, cell
transport and cell division in all eukaryotes. The regulation of the microtubule system …

In all eukaryotes, a microtubule-based structure known as the spindle is responsible for
accurate chromosome segregation during cell division. Spindle assembly and function …

Stathmin is the founding member of a family of proteins that play critically important roles in
the regulation of the microtubule cytoskeleton. Stathmin regulates microtubule dynamics by …

▪ Abstract The microtubule cytoskeleton is a highly regulated system. At different times in the
cell cycle and positions within the organism, microtubules can be very stable or highly …

The past several years have seen major advances in our understanding of the mechanisms
of microtubule destabilization by oncoprotein18/stathmin (Op18/stathmin) and related …

Microtubules (MTs), key components of the cytoskeleton, are dynamic polymers of tubulin
that form a well-organized network of polarized tube filaments. MT dynamics are highly …

Introduction: Stathmin is a microtubule-destabilizing phosphoprotein, firstly identified as the
downstream target of many signal transduction pathways. Several studies then indicated …

Stat3 is a member of the signal transducer and activator of transcription family, which is
important in cytokine signaling. Gene ablation studies have revealed a requirement for Stat3 …

Emerging evidences suggest that cyclin-dependent kinase inhibitors (CKIs) can regulate
cellular functions other than cell cycle progression, such as differentiation and migration …