[HTML][HTML] Mitochondrial complex I ROS production and redox signaling in hypoxia

CN Okoye, SA Koren, AP Wojtovich - Redox biology, 2023 - Elsevier
Mitochondria are a main source of cellular energy. Oxidative phosphorylation (OXPHOS) is
the major process of aerobic respiration. Enzyme complexes of the electron transport chain …

Carotid body chemoreceptors: physiology, pathology, and implications for health and disease

R Iturriaga, J Alcayaga, MW Chapleau… - Physiological …, 2021 - journals.physiology.org
The carotid body (CB) is the main peripheral chemoreceptor for arterial respiratory gases O2
and CO2 and pH, eliciting reflex ventilatory, cardiovascular, and humoral responses to …

Astrocytes monitor cerebral perfusion and control systemic circulation to maintain brain blood flow

N Marina, IN Christie, A Korsak, M Doronin… - Nature …, 2020 - nature.com
Astrocytes provide neurons with essential metabolic and structural support, modulate
neuronal circuit activity and may also function as versatile surveyors of brain milieu, tuned to …

Astrocytes regulate brain extracellular pH via a neuronal activity-dependent bicarbonate shuttle

SM Theparambil, PS Hosford, I Ruminot… - Nature …, 2020 - nature.com
Brain cells continuously produce and release protons into the extracellular space, with the
rate of acid production corresponding to the levels of neuronal activity and metabolism …

Astrocytes and behavior

P Kofuji, A Araque - Annual review of neuroscience, 2021 - annualreviews.org
Animal behavior was classically considered to be determined exclusively by neuronal
activity, whereas surrounding glial cells such as astrocytes played only supportive roles …

Astrocyte regulation of neural circuit activity and network states

JF Oliveira, A Araque - Glia, 2022 - Wiley Online Library
Astrocytes are known to influence neuronal activity through different mechanisms, including
the homeostatic control of extracellular levels of ions and neurotransmitters and the …

Regulation of myelin structure and conduction velocity by perinodal astrocytes

DJ Dutta, DH Woo, PR Lee, S Pajevic… - Proceedings of the …, 2018 - National Acad Sciences
The speed of impulse transmission is critical for optimal neural circuit function, but it is
unclear how the appropriate conduction velocity is established in individual axons. The …

The retrotrapezoid nucleus: central chemoreceptor and regulator of breathing automaticity

PG Guyenet, RL Stornetta, GMPR Souza… - Trends in …, 2019 - cell.com
The ventral surface of the rostral medulla oblongata has been suspected since the 1960s to
harbor central respiratory chemoreceptors [ie, acid-activated neurons that regulate breathing …

Astrocyte alterations in neurodegenerative pathologies and their modeling in human induced pluripotent stem cell platforms

M Oksanen, S Lehtonen, M Jaronen… - Cellular and Molecular …, 2019 - Springer
Astrocytes are the most abundant cell type in the brain. They were long considered only as
passive support for neuronal cells. However, recent data have revealed many active roles …

[HTML][HTML] The pathobiology of myalgic encephalomyelitis/chronic fatigue syndrome: the case for neuroglial failure

H Renz-Polster, ME Tremblay, D Bienzle… - Frontiers in cellular …, 2022 - frontiersin.org
Although myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) has a specific and
distinctive profile of clinical features, the disease remains an enigma because causal …