The progression of cancer involves not only the gradual evolution of cells by mutations in
DNA but also alterations in the gene expression induced by those mutations and input from …

BTB domain and CNC homology 1 (BACH1) is a transcription factor that is highly expressed
in tumors including breast and lung, relative to their non-tumor tissues. BACH1 is known to …

The GeneCards® database of human genes was launched in 1997 and has expanded
since then to encompass gene-centric, disease-centric, and pathway-centric entities and …

Cerebrovascular dysregulation is a hallmark of Alzheimer's disease (AD), but the changes
that occur in specific cell types have not been fully characterized. Here, we profile single …

Millions of cardiomyocytes die immediately after myocardial infarction, regardless of whether
the culprit coronary artery undergoes prompt revascularization. Residual ischaemia in the …

Ischemic stroke (IS) is a cerebrovascular disease causing high rates of disability and fatality.
In recent years, the concept of the neurovascular unit (NVU) has been accepted by an …

The breakdown of the blood–brain barrier, which develops early in Alzheimer's disease
(AD), contributes to cognitive impairment. Exercise not only reduces the risk factors for AD …

Diabetes mellitus increases the risk and accelerates the course of peripheral artery disease,
making patients more susceptible to ischemic events and infections and delaying tissue …

Background: Diabetes mellitus is a prevalent public health problem that affects about one-
third of the US population and leads to serious vascular complications with increased risk for …

Angiogenesis is rapidly initiated in response to pathological conditions and is a key target
for pharmaceutical intervention in various malignancies. Anti-angiogenic therapy has …