N-Heterocyclic carbenes (NHCs) are cyclic carbenes bearing at least one R-amino
substituent. 1 The most common subclasses of NHCs are represented in Chart 1. Early work …

Carbenes are perhaps the most versatile reactive intermediates in chemistry. Since the
original visions of “methylene” by Dumas 1 in 1835 and a generalization of this vision by Nef …

Electronic and steric ligand effects both play major roles in organometallic chemistry and
consequently in metal-mediated catalysis. Quantifying such parameters is of interest to …

This critical review is an updated survey of metal–carbenes as potential anticancer
chemotherapeutics. We report on the recent advances in the discovery of N-heterocyclic …

Hydrosilylation of C–C multiple bonds is one of the most important applications of
homogeneous catalysis in industry. The reaction is characterized by its atom-efficiency …

Since the isolation and crystallographic characterization of the first stable N-heterocyclic
carbene in early 1991, 1 nucleophilic diaminocarbenes (also known as “Arduengotype” …

N-Heterocyclic carbene complexes of platinum (II) have been synthesized, notably
monocarbene complexes cis-[(IPr) Pt (dmso)(Cl) 2], 6, cis-[(IMes) Pt (dmso)(Cl) 2], 7, cis …

N-Heterocyclic carbene (NHC) platinum complexes have been highlighted as a promising
and original platform for building new cytotoxic drugs of the cisplatin series. Mixed NHC …

Controlling the synthesis of stable metal nanoparticles in water is a current challenge in
nanochemistry. The strategy presented herein uses sulfonated N‐heterocyclic carbene …

Despite significant progress in the area of C–H bond functionalization of arenes, no general
method has been reported for the functionalization of C–H bonds at the sterically …