The transcription factor NF-κB is a central mediator of inflammation with multiple links to
thrombotic processes. In this review, we focus on the role of NF-κB signaling in cell types …

Obesity is characterized by the excessive deposition of fat that may interfere with the normal
metabolic process of the body. It is a chronic condition associated with various metabolic …

The role of platelet adhesion, activation, and aggregation in acute atherothrombotic events
such as myocardial infarction and stroke is well established. There is increasing evidence …

Psoriasis is a chronic inflammatory skin disease with a prevalence of 0.14% to 1.99%. The
underlying pathology is mainly driven by the abnormal immune responses including …

Chronic inflammation drives the development of atherosclerosis. Despite optimal treatment
of classical cardiovascular risk factors, a substantial portion of the population has elevated …

Monocyte extravasation into the vessel wall is a key step in atherogenesis. It is still elusive
how monocytes transmigrate through the endothelial cell (EC) monolayer at atherosclerosis …

Despite great efforts in stroke research, disability and recurrence rates in ischaemic stroke
remain unacceptably high. To address this issue, one potential target for novel therapeutics …

Systemic lupus erythematosus (SLE), systemic sclerosis (SSc), and small vessel vasculitis
are three autoimmune diseases frequently manifested in the skin. They share common …

Aims High levels of glucose and reactive carbonyl intermediates of its degradation pathway
such as methylglyoxal (MG) may contribute to diabetic complications partly via increased …

Inflammation is a major contributor to tubular epithelium injury in kidney disorders, and the
involvement of blood platelets in driving inflammation is increasingly stressed. CD154, the …