Protein kinase CK2 ('casein kinase II') has traditionally been classified as a messenger-
independent protein serine/threonine kinase that is typically found in tetrameric complexes …

CK2 is a highly conserved, ubiquitously expressed protein serine/threonine kinase present
in all eukaryotes. Circumscribed as having a vast array of substrates located in a number of …

Minutes after DNA damage, the variant histone H2AX is phosphorylated by protein kinases
of the phosphoinositide kinase family, including ATM, ATR or DNA-PK. Phosphorylated (γ) …

Protein kinase CK2 (formerly casein kinase II), an enzyme that participates in a wide variety
of cellular processes, has traditionally been classified as a stable tetrameric complex …

Protein kinase CK2 is a multifunctional enzyme which has long been described as a stable
heterotetrameric complex resulting from the association of two catalytic (α or α′) and two …

Within the last decade, 40 crystal structures corresponding to protein kinase CK2 (former
name 'casein kinase 2'), to its catalytic subunit CK2α and to its regulatory subunit CK2β were …

The peptidyl-prolyl isomerase Pin1 interacts in a phosphorylation-dependent manner with
several proteins involved in cell cycle events. In this study, we demonstrate that Pin1 …

X-ray crystallography studies, as well as live-cell fluorescent imaging, have recently
challenged the traditional view of protein kinase CK2. Unbalanced expression of catalytic …

Recently protein kinases have emerged as some of the most promising drug targets; and
therefore, pharmaceutical strategies have been developed to inhibit kinases in the treatment …

Protein kinase CK2 is a protein serine/threonine kinase that exhibits elevated expression in
a number of cancers and displays oncogenic activity in mice. The regulatory CK2β subunit …