In human beings, two forms of GnRH, termed GnRH-I and GnRH-II, encoded by separate
genes have been identified. Although these hormones share comparable cDNA and …

Ovarian epithelial cancer (OEC) accounts for 90% of all ovarian cancers and is the leading
cause of death from gynecological cancers in North America and Europe. Despite its clinical …

We studied the roles of the phosphatidylinositol 3-kinase (PI-3K)-protein kinase B/Akt-BAD
cascade in both cisplatin-resistant Caov-3 and-sensitive A2780 human ovarian cancer cell …

The crucial role of pituitary GnRH receptors (GnRH-R) in the control of reproductive
functions is well established. These receptors are the target of GnRH agonists (through …

The hypothalamic gonadotropin-releasing hormone (GnRH) is a key regulator of the
reproductive system, triggering the synthesis and release of LH and FSH in the pituitary …

Gonadotropin‐releasing hormone (GnRH) has historically been known as a pituitary
hormone; however, in the past few years, interest has been raised in locally produced …

We studied the roles of the phosphatidylinositol 3-kinase (PI-3K)-Akt-BAD cascade, ERK-
BAD cascade, and Akt-Raf-1 cascade in the paclitaxel-resistant SW626 human ovarian …

It is now well known that different forms of GnRH coexist in the same vertebrate species. In
humans, two forms of GnRH have been identified so far. The first form corresponds to the …

Geoffrey Wingfield Harris' demonstration of hypothalamic hormones regulating pituitary
function led to their structural identification and therapeutic utilization in a wide spectrum of …

Objective: Several recent reports have demonstrated the expression of luteinizing hormone-
releasing hormone receptors by human ovarian and endometrial cancers. Controversy …