Wider use of clozapine, one of the most effective antipshychotic drugs, is precluded by its
propensity to cause agranulocytosis. Currently, clozapine is used for treatment-resistant …

Clozapine, a dibenzodiazepine developed in 1961, is a multireceptorial atypical
antipsychotic approved for the treatment of resistant schizophrenia. Since its introduction, it …

Drug-induced lupus (DIL) is a side effect of long-term use of up to 100 medications.
Rheumatologic symptoms including fever, malaise, weight loss, polyarticular arthralgias …

Neutropenia is defined as the reduction in the absolute number of neutrophils in the blood
circulation. Acute neutropenia is a relatively frequent finding, whereas disorders of …

A number of therapeutic drugs with different structures and mechanisms of action have been
reported to undergo metabolic activation by Phase I or Phase II drug-metabolizing enzymes …

Idiosyncratic drug-induced agranulocytosis or acute neutrope... : Current Opinion in
Hematology Idiosyncratic drug-induced agranulocytosis or acute neutropenia : Current Opinion …

Clozapine remains the drug of choice for treatment resistant schizophrenia, but is associated
with potentially life threatening side effects, including agranulocytosis and myocarditis …

Drug-induced lupus erythematosus (DILE) is defined as an entity characterized by clinical
manifestations and immunopathological serum findings similar to those of idiopathic lupus …

Drug-induced lupus erythematosus (DILE) is a lupus-like illness that has been recognized
as an entity under environmentally-induced lupus erythematosus, where other agents such …

Non–chemotherapy idiosyncratic drug–induced neutropenia (IDIN) is a relatively rare but
potentially fatal disorder that occurs in susceptible individuals, with an incidence of 2.4 to …