Conformation and vibrational spectroscopic analysis of 2, 6-bis (4-fluorophenyl)-3, 3-dimethylpiperidin-4-one (BFDP) by DFT method: A potent anti-Parkinson's, anti …

T Arumugam, A Ramalingam, AR Guerroudj… - Heliyon, 2023 - cell.com
Abstract The potential of 2, 6-bis (4-fluorophenyl)-3, 3-dimethylpiperidin-4-one (BFDP) as an
anti-Parkinson's, anti-lung cancer, and anti-human infectious agent was extensively …

[HTML][HTML] Bisindole Compounds—Synthesis and Medicinal Properties

M Marinescu - Antibiotics, 2024 - mdpi.com
The indole nucleus stands out as a pharmacophore, among other aromatic heterocyclic
compounds with remarkable therapeutic properties, such as benzimidazole, pyridine …

Study of new carbonitrile as an anti-muscular dystrophy agent: crystal, vibrational spectroscopy, molecular docking, electronic and intermolecular interaction …

A Ramalingam, C Duraisamy, H Louis… - Journal of Molecular …, 2024 - Elsevier
Muscular dystrophy, a genetically induced and highly lethal disease, necessitates urgent
curative solutions. Many therapeutic drugs for this condition incorporate heterocyclic …

Spectroscopic study, Hirshfeld surface, DFT, in-silico molecular docking and ADMET studies of 2, 6-bis (4-chlorophenyl)-3-isopropylpiperidin-4-one (BCIP): a potent …

A Ramalingam, S Sambandam, H Louis… - Journal of Molecular …, 2023 - Elsevier
In this present study, the possibility of using 2, 6-bis (4-chlorophenyl)-3-isopropylpiperidin-4-
one (BCIP) as an antiviral agent against HIV was carefully evaluated. In order to achieve …

Visible light-assisted H4 [PW11VO40] catalysed synthesis of bis (indolyl) methanes

G Jagannivasan, GN Nair, S Haridas - Molecular Catalysis, 2023 - Elsevier
The development of novel synthetic protocols for organic transformations is a key challenge
in fine chemical synthesis. A novel light-assisted protocol for the synthesis of bis (indolyl) …

Study of new p-tolylpiperidin-4-one as an anti-Parkinson agent: Synthesis, spectral, XRD-crystal, in silico study, electronic and intermolecular interaction investigations …

A Ramalingam, T Arumugam, A Sagaama… - Materials Chemistry and …, 2024 - Elsevier
This study thoroughly investigated the potential of using 3, 3-dimethyl-2, 6-di-p-tolylpiperidin-
4-one,(DMeTP) as an anti-Parkinson medicine against Parkinson's disease. To accomplish …

[HTML][HTML] Spectroscopic characterization, electronic transitions and pharmacodynamic analysis of 1-Phenyl-1, 3-butanedione: An effective agent for antipsychotic …

M Lawrence, EI Paulraj, P Rajesh - Chemical Physics Impact, 2023 - Elsevier
The density functional theory with the Becke, 3-parameter, Lee–Yang–Parr (B3LYP)
technique and the 6-311++ G (d, p) basis set is used to optimize the compound 1-Phenyl-1 …

Merging Photoredox with Nickel Catalysis for Decarboxylative Arylation of Indole‐3‐Acetic Acids with Aryl Halides

A Guin, S Bera, VB Pathi, B Banerji - ChemPhotoChem, 2024 - Wiley Online Library
Late‐stage functionalization of indoles can be a valuable strategy for modifying different
existing indolyl‐drugs and natural products to get their new analogues. In this study, we …

Synthesis of 3-Aminoalkylated Indoles Using Heterogeneous MgFe2O4 Nanoparticles Under Microwave Irradiation in One-Pot Three-Component System

D Gupta, PP Singh - Synthesis, 2023 - thieme-connect.com
A series of 3-aminoalkylated indoles are efficiently synthesised in a one-pot three-
component reaction under microwave irradiation. Magnesium ferrite (MgFe 2 O 4) …

[PDF][PDF] Chemical Physics Impact

M Lawrence, EI Paulraj, P Rajesh - researchgate.net
The density functional theory with the Becke, 3-parameter, Lee–Yang–Parr (B3LYP)
technique and the 6-311++ G (d, p) basis set is used to optimize the compound 1-Phenyl-1 …