Recent advances in characterization of citrullination and its implication in human disease research: From method development to network integration
Post‐translational modifications (PTM) of proteins increase the functional diversity of the
proteome and have been implicated in the pathogenesis of numerous diseases. The most …
proteome and have been implicated in the pathogenesis of numerous diseases. The most …
Neutrophil attachment via Mac-1 (αMβ2; CD11b/CD18; CR3) integrins induces PAD4 deimination of profilin and histone H3
I Neeli, M Moarefian, J Kuseladass… - … of the Royal …, 2023 - royalsocietypublishing.org
Neutrophil adhesion to endothelia, entry into tissues and chemotaxis constitute essential
steps in the immune response to infections that drive inflammation. Neutrophils bind to other …
steps in the immune response to infections that drive inflammation. Neutrophils bind to other …
Mass Spectrometry-Based Precise Identification of Citrullinated Histones via Limited Digestion and Biotin Derivative Tag Enrichment
Histone citrullination is an essential epigenetic post-translational modification (PTM) that
affects many important physiological and pathological processes, but effective tools to study …
affects many important physiological and pathological processes, but effective tools to study …
Development of antibody-based tools to study PAD4 protein dynamics and cell surface interactions
S Kong - 2024 - escholarship.org
The development of engineered biologics as both tools and therapeutic molecules have
transformed the scientific landscape tremendously. Due to their increased specificity …
transformed the scientific landscape tremendously. Due to their increased specificity …
Antibody Engineering to Modulate PAD4 Activity and Investigate Cell Surface Citrullination
S Kong - 2024 - search.proquest.com
The development of engineered biologics as both tools and therapeutic molecules have
transformed the scientific landscape tremendously. Due to their increased specificity …
transformed the scientific landscape tremendously. Due to their increased specificity …
Global profiling of arginine reactivity and ligandability in the human proteome
G Li, Y Wang, S Xie, T Hu, L Zhu, Y Zhai, Y Li, C Xu… - 2024 - researchsquare.com
Covalent small molecules targeting nucleophilic amino acids have emerged as a rapidly
advancing frontier in covalent drug development, with a primary focus on cysteine and lysine …
advancing frontier in covalent drug development, with a primary focus on cysteine and lysine …
[PDF][PDF] Structural and functional studies of protein citrullination
M Grißmann - unipub.uni-graz.at
Zusammenfassung Bei der posttranslationalen Modifikation Citrullinierung werden
Argininreste in Proteinen in Citrullinreste umgewandelt. Diese Umwandlung wird durch die …
Argininreste in Proteinen in Citrullinreste umgewandelt. Diese Umwandlung wird durch die …