X-ray crystallography is a critical tool in the study of biological systems. It is able to provide
information that has been a prerequisite to understanding the fundamentals of life. It is also a …

The number of macromolecular structures deposited in the Protein Data Bank now
approaches 100 000, with the vast majority of them determined by crystallographic methods …

The refinement and validation of a crystallographic structure model is the last step before the
coordinates and the associated data are submitted to the Protein Data Bank (PDB). The …

Deubiquitinating enzymes (DUBs) remove ubiquitin (Ub) from Ub-conjugated substrates to
regulate the functional outcome of ubiquitylation. Here we report the discovery of a new …

The programs SHELXC, SHELXD and SHELXE are designed to provide simple, robust and
efficient experimental phasing of macromolecules by the SAD, MAD, SIR, SIRAS and RIP …

A new approach that integrates data collection, data reduction, phasing and model building
significantly accelerates the process of structure determination and on average minimizes …

ARP/wARP is a software suite to build macromolecular models in X-ray crystallography
electron density maps. Structural genomics initiatives and the study of complex …

Deubiquitinating enzymes (DUBs) are important regulators of ubiquitin signaling. Here, we
report the discovery of deubiquitinating activity in ZUFSP/C6orf113. High-resolution crystal …

IL MILIONEIl Milione is the title of the book by Marco Polo, dictated to Rustichello da Pisa in
1298 in the Genova prison where Marco was imprisoned after a naval battle between …

The number of macromolecular structures solved and deposited in the Protein Data Bank
(PDB) is higher than 40 000. Using this information in macromolecular crystallography (MX) …