Natural killer cells: from innate to adaptive features
AM Mujal, RB Delconte, JC Sun - Annual review of immunology, 2021 - annualreviews.org
Natural killer (NK) cells are innate lymphocytes that provide critical host defense against
pathogens and cancer. Originally heralded for their early and rapid effector activity, NK cells …
pathogens and cancer. Originally heralded for their early and rapid effector activity, NK cells …
The broad spectrum of human natural killer cell diversity
Natural killer (NK) cells provide protection against infectious pathogens and cancer. For
decades it has been appreciated that two major NK cell subsets (CD56 bright and CD56 …
decades it has been appreciated that two major NK cell subsets (CD56 bright and CD56 …
Peptide-specific recognition of human cytomegalovirus strains controls adaptive natural killer cells
Natural killer (NK) cells are innate lymphocytes that lack antigen-specific rearranged
receptors, a hallmark of adaptive lymphocytes. In some people infected with human …
receptors, a hallmark of adaptive lymphocytes. In some people infected with human …
Natural killer cell memory in infection, inflammation and cancer
A Cerwenka, LL Lanier - Nature Reviews Immunology, 2016 - nature.com
Immunological memory can be defined as a quantitatively and qualitatively enhanced
immune response upon rechallenge. For natural killer (NK) cells, two main types of memory …
immune response upon rechallenge. For natural killer (NK) cells, two main types of memory …
Epigenetic modification and antibody-dependent expansion of memory-like NK cells in human cytomegalovirus-infected individuals
Summary Long-lived" memory-like" NK cells have been identified in individuals infected by
human cytomegalovirus (HCMV), but little is known about how the memory-like NK cell pool …
human cytomegalovirus (HCMV), but little is known about how the memory-like NK cell pool …
Balancing natural killer cell activation through paired receptors
L Martinet, MJ Smyth - Nature Reviews Immunology, 2015 - nature.com
Natural killer (NK) cells are innate lymphocytes that are crucial for the control of infections
and malignancies. NK cells express a variety of inhibitory and activating receptors that …
and malignancies. NK cells express a variety of inhibitory and activating receptors that …
Natural killer cell memory
TE O'Sullivan, JC Sun, LL Lanier - Immunity, 2015 - cell.com
Natural killer (NK) cells have historically been considered short-lived cytolytic cells that can
rapidly respond against pathogens and tumors in an antigen-independent manner and then …
rapidly respond against pathogens and tumors in an antigen-independent manner and then …
Natural killer cell-mediated immunosurveillance of human cancer
KJ Malmberg, M Carlsten, A Björklund, E Sohlberg… - Seminars in …, 2017 - Elsevier
The contribution of natural killer (NK) cells to immunosurveillance of human cancer remains
debatable. Here, we discuss advances in several areas of human NK cell research, many of …
debatable. Here, we discuss advances in several areas of human NK cell research, many of …
Natural killer cell specificity for viral infections
Natural killer (NK) cells are lymphocytes that contribute to the early immune responses to
viruses. NK cells are innate immune cells that do not express rearranged antigen receptors …
viruses. NK cells are innate immune cells that do not express rearranged antigen receptors …
NK cell responses to cytomegalovirus infection lead to stable imprints in the human KIR repertoire and involve activating KIRs
V Béziat, LL Liu, JA Malmberg… - Blood, The Journal …, 2013 - ashpublications.org
Human natural killer (NK) cells are functionally regulated by killer cell immunoglobulin-like
receptors (KIRs) and their interactions with HLA class I molecules. As KIR expression in a …
receptors (KIRs) and their interactions with HLA class I molecules. As KIR expression in a …