Abstract THY1 (CD90) is a 25–37-kDa heavily N-glycosylated, glycophosphatidylinositol
(GPI) anchored cell surface protein. It is usually expressed on thymocytes, mesenchymal …

A novel signaling mechanism is described through which extracellular signals and
intracellular signaling pathways regulate proliferation, growth, differentiation, and other …

Both late-gestation and adult human forebrain contain large numbers of oligodendrocyte
progenitor cells (OPCs). These cells may be identified by their A2B5+ PSA-NCAM …

The proliferative ventricular zone (VZ) is the main source of projection neurons for the
overlying cerebral neocortex. The number and diversity of neocortical neurons is …

How a naive human neuroepithelial cell becomes an electrophysiologically active neuron
remains unknown. Here, we describe the early physiological development of neurons …

Background Alzheimer's disease (AD) is an inexorable neurodegenerative disease that
commonly occurs in the elderly. The cognitive impairment caused by AD is associated with …

Several laboratories have begun evaluating human ES (hES) cell lines; however, direct
comparisons between different hES cell lines have not been performed. We have …

Multipotent neural stem cells (NSCs) present in the developing neural tube (E10. 5,
neuroepithelial cells; NEP) were examined for the expression of candidate stem cell …

Polychlorinated biphenyls (PCBs) are ubiquitous environmental chemicals that accumulate
in adipose tissues over the food chain. Epidemiologic studies have indicated that PCBs …

Neural stem cells (NSCs) have the ability to self‐renew, and are capable of differentiating
into neurones, astrocytes and oligodendrocytes. Such cells have been isolated from the …