Temperature is a universal cue and regulates many essential processes ranging from
enzymatic reactions to species migration. Due to the profound impact of temperature on …

Caenorhabditis elegans lives in a complex habitat in which they routinely experience large
fluctuations in temperature, and encounter physical obstacles that vary in size and …

We present an imaging system for pan-neuronal recording in crawling Caenorhabditis
elegans. A spinning disk confocal microscope, modified for automated tracking of the C …

Neuroscience relies on techniques for imaging the structure and dynamics of neural circuits,
but the cell bodies of individual neurons are often obscured by overlapping fluorescence …

Learning is an essential biological process for survival since it facilitates behavioural
plasticity in response to environmental changes. This process is mediated by a wide variety …

Simple innate behavior is often described as hard-wired and largely inflexible. Here, we
show that the avoidance of hot temperature, a simple innate behavior, contains unexpected …

In neurons, defects in autophagosome clearance have been associated with
neurodegenerative disease. Yet, the mechanisms that coordinate trafficking and clearance …

Neurons modify their transcriptomes in response to an animal's experience. How specific
experiences are transduced to modulate gene expression and precisely tune neuronal …

Neural plasticity, the ability of neurons to change their properties in response to
experiences, underpins the nervous system's capacity to form memories and actuate …

Soil-transmitted parasitic nematodes infect over one billion people and cause devastating
morbidity worldwide. Many of these parasites have infective larvae that locate hosts using …