The potential role of PPARs in the fetal origins of adult disease

J Guo, J Wu, Q He, M Zhang, H Li, Y Liu - Cells, 2022 - mdpi.com
The fetal origins of adult disease (FOAD) hypothesis holds that events during early
development have a profound impact on one's risk for the development of future adult …

Endothelial cell clonality, heterogeneity and dysfunction in pulmonary arterial hypertension

G Newcomb, L Farkas - Frontiers in Medicine, 2023 - frontiersin.org
Our understanding of the pathophysiology of pulmonary arterial hypertension (PAH) has
evolved over recent years, with the recognition that endothelial cell (EC) dysfunction and …

CXCL10 deficiency limits macrophage infiltration, preserves lung matrix, and enables lung growth in bronchopulmonary dysplasia

DV Hirani, F Thielen, S Mansouri… - Inflammation and …, 2023 - Springer
Preterm infants with oxygen supplementation are at high risk for bronchopulmonary
dysplasia (BPD), a neonatal chronic lung disease. Inflammation with macrophage activation …

Characterizing and quenching autofluorescence in fixed mouse adrenal cortex tissue

N Sakr, O Glazova, L Shevkova, N Onyanov… - International Journal of …, 2023 - mdpi.com
Tissue autofluorescence of fixed tissue sections is a major concern of fluorescence
microscopy. The adrenal cortex emits intense intrinsic fluorescence that interferes with …

HO-1/autophagic flux axis alleviated sepsis-induced acute lung injury via inhibiting NLRP3 inflammasome

L Shutong, J Yu, W Jia, D Huafei, Y Shifan, W Huili… - Cellular …, 2022 - Elsevier
Among the multiple organ injuries induced by sepsis, acute lung injury (ALI) triggered by an
excessive inflammatory response is one of the main causes contributing to patient death …

Identification of related-genes of T cells in lung tissue of chronic obstructive pulmonary disease based on bioinformatics and experimental validation

T Xue, F Dong, J Gao, X Zhong - Scientific Reports, 2024 - nature.com
T cells are one of the main cell types shaping the immune microenvironment in chronic
obstructive pulmonary disease (COPD). They persist andplay cytotoxic roles. The purpose of …

The importance of translational science within the respiratory field

S Meiners, NL Reynaert, AM Matthaiou, R Rajesh… - Breathe, 2024 - Eur Respiratory Soc
The Translational Science Working Group at the European Respiratory Society (ERS) aims
to bridge the gap between basic and clinical science by providing a platform where …

ERS International Congress 2023: highlights from the Paediatrics Assembly

SJH Vijverberg, A Kampouras… - ERJ open …, 2024 - Eur Respiratory Soc
Respiratory health in children is essential for general wellbeing and healthy development in
the short and long term. It is well known that many respiratory diseases in adulthood have …

Perinatal obesity sensitizes for premature kidney aging signaling

J Selle, K Bohl, K Höpker, R Wilke, K Dinger… - International Journal of …, 2023 - mdpi.com
Chronic Kidney Disease (CKD), a global health burden, is strongly associated with age-
related renal function decline, hypertension, and diabetes, which are all frequent …

[HTML][HTML] The Role of Early Child Nutrition in Pulmonary Hypertension—A Narrative Review

AC Luca, C Stoica, C Diaconescu, E Țarcă, ST Roșu… - Children, 2024 - mdpi.com
Pulmonary hypertension is a complex condition that has distinct characteristics in pediatric
populations. This review explores the important role of early childhood nutrition in the …