[HTML][HTML] Influence of tryptophan and serotonin on mood and cognition with a possible role of the gut-brain axis
TA Jenkins, JCD Nguyen, KE Polglaze, PP Bertrand - Nutrients, 2016 - mdpi.com
The serotonergic system forms a diffuse network within the central nervous system and plays
a significant role in the regulation of mood and cognition. Manipulation of tryptophan levels …
a significant role in the regulation of mood and cognition. Manipulation of tryptophan levels …
[HTML][HTML] Gut microbial metabolites in depression: understanding the biochemical mechanisms
Gastrointestinal and central function are intrinsically connected by the gut microbiota, an
ecosystem that has co-evolved with the host to expand its biotransformational capabilities …
ecosystem that has co-evolved with the host to expand its biotransformational capabilities …
The kynurenine pathway in major depressive disorder, bipolar disorder, and schizophrenia: a meta-analysis of 101 studies
The importance of tryptophan as a precursor for neuroactive compounds has long been
acknowledged. The metabolism of tryptophan along the kynurenine pathway and its …
acknowledged. The metabolism of tryptophan along the kynurenine pathway and its …
Depression: the case for a monoamine deficiency
PL Delgado - Journal of clinical Psychiatry, 2000 - psychiatrist.com
The monoamine hypothesis of depression predicts that the underlying pathophysiologic
basis of depression is a depletion in the levels of serotonin, norepinephrine, and/or …
basis of depression is a depletion in the levels of serotonin, norepinephrine, and/or …
Mood is indirectly related to serotonin, norepinephrine and dopamine levels in humans: a meta-analysis of monoamine depletion studies
HG Ruhé, NS Mason, AH Schene - Molecular psychiatry, 2007 - nature.com
Dysfunction in the monoamine systems of serotonin (5-HT), norepinephrine (NE) and
dopamine (DA) may causally be related to major depressive disorder (MDD). Monoamine …
dopamine (DA) may causally be related to major depressive disorder (MDD). Monoamine …
Cytokine-induced sickness behaviour: mechanisms and implications
Sickness behaviour represents the expression of the adaptive reorganization of the priorities
of the host during an infectious episode. This process is triggered by pro-inflammatory …
of the host during an infectious episode. This process is triggered by pro-inflammatory …
An excitatory synapse hypothesis of depression
Depression is a common cause of mortality and morbidity, but the biological bases of the
deficits in emotional and cognitive processing remain incompletely understood. Current …
deficits in emotional and cognitive processing remain incompletely understood. Current …
Central monoamines and their role in major depression
AS Elhwuegi - Progress in Neuro-Psychopharmacology and …, 2004 - Elsevier
The role of the monoamines serotonin and noradrenaline in mental illnesses including
depression is well recognized. All antidepressant drugs in clinical use increase acutely the …
depression is well recognized. All antidepressant drugs in clinical use increase acutely the …
Serotonergic function, two-mode models of self-regulation, and vulnerability to depression: what depression has in common with impulsive aggression.
Evidence from diverse literatures supports the viewpoint that two modes of self-regulation
exist, a lower-order system that responds quickly to associative cues of the moment and a …
exist, a lower-order system that responds quickly to associative cues of the moment and a …
The role of serotonin in human mood and social interaction: insight from altered tryptophan levels
Alterations in brain tryptophan levels cause changes in brain serotonin synthesis, and this
has been used to study the implication of altered serotonin levels in humans. In the acute …
has been used to study the implication of altered serotonin levels in humans. In the acute …