Medication-assisted treatment for opioid-use disorder

TS Oesterle, NJ Thusius, TA Rummans… - Mayo Clinic …, 2019 - Elsevier
Abstract The United States is in the midst of a national opioid epidemic. Physicians are
encouraged both to prevent and treat opioid-use disorders (OUDs). Although there are 3 …

Benzylisoquinoline alkaloid biosynthesis in opium poppy: an update

A Singh, IM Menéndez-Perdomo, PJ Facchini - Phytochemistry Reviews, 2019 - Springer
For nearly eight millennia, opium poppy (Papaver somniferum) has been bred and cultivated
for therapeutic purposes. The medicinal properties of the plant are conferred by specialized …

Prospective, randomized, double‐blind assessment of topical bakuchiol and retinol for facial photoageing

S Dhaliwal, I Rybak, SR Ellis, M Notay… - British Journal of …, 2019 - academic.oup.com
Background Bakuchiol is a phytochemical that has demonstrated cutaneous antiageing
effects when applied topically. Early studies have suggested that bakuchiol is a functional …

Medical gas therapy for tissue, organ, and CNS protection: a systematic review of effects, mechanisms, and challenges

RD Zafonte, L Wang, CA Arbelaez… - Advanced …, 2022 - Wiley Online Library
Gaseous molecules have been increasingly explored for therapeutic development. Here,
following an analytical background introduction, a systematic review of medical gas …

Plant-derived natural products: a source for drug discovery and development

N Chaachouay, L Zidane - Drugs and Drug Candidates, 2024 - mdpi.com
For thousands of years, nature has been a source of medical substances, and an
astounding numeral of contemporary remedies have been identified from natural origins …

Mechanisms of central hypogonadism

TM Barber, I Kyrou, G Kaltsas, AB Grossman… - International Journal of …, 2021 - mdpi.com
Reproductive function depends upon an operational hypothalamo–pituitary–gonadal (HPG)
axis. Due to its role in determining survival versus reproductive strategies, the HPG axis is …

Synthetic opioids: a review and clinical update

A Shafi, AJ Berry, H Sumnall… - Therapeutic …, 2022 - journals.sagepub.com
The term 'opioids' refers to both the natural compounds ('opiates') which are extracted from
the opium poppy plant (Papaver somniferum) and their semi-synthetic and synthetic …

DARK classics in chemical neuroscience: fentanyl

SM Burns, CW Cunningham… - ACS chemical …, 2018 - ACS Publications
Fentanyl rose to prominence as an alternative analgesic to morphine nearly 50 years ago;
today, fentanyl has re-emerged as a dangerous recreational substance. The increased …

[HTML][HTML] Alkaloids: therapeutic potential against human coronaviruses

BC Fielding, C da Silva Maia Bezerra Filho, NSM Ismail… - Molecules, 2020 - mdpi.com
Alkaloids are a class of natural products known to have wide pharmacological activity and
have great potential for the development of new drugs to treat a wide array of pathologies …

Pharmacological treatments and therapeutic drug monitoring in patients with chronic pain

F De Rosa, B Giannatiempo, B Charlier, A Coglianese… - Pharmaceutics, 2023 - mdpi.com
Pain is an unpleasant sensory and emotional experience that affects every aspect of a
patient's life and which may be treated through different pharmacological and non …