The burden of inflammatory bowel disease in Europe in 2020

M Zhao, L Gönczi, PL Lakatos… - Journal of Crohn's and …, 2021 - academic.oup.com
New data suggest that incidence and prevalence of inflammatory bowel diseases [IBD] are
still increasing worldwide, and approximately 0.2% of the European population suffer from …

Evolving epidemiology of IBD

JW Windsor, GG Kaplan - Current gastroenterology reports, 2019 - Springer
Abstract Purpose of Review Once thought a disease of Western civilizations, the
inflammatory bowel diseases (IBD) impose a global burden, now penetrating populations in …

Risk of serious and opportunistic infections associated with treatment of inflammatory bowel diseases

J Kirchgesner, M Lemaitre, F Carrat, M Zureik… - Gastroenterology, 2018 - Elsevier
Background & Aims The risk of infection associated with tumor necrosis factor antagonists
(anti-TNF) and thiopurines (combination therapy) is uncertain. We assessed the risk of …

Association between use of thiopurines or tumor necrosis factor antagonists alone or in combination and risk of lymphoma in patients with inflammatory bowel disease

M Lemaitre, J Kirchgesner, A Rudnichi, F Carrat… - Jama, 2017 - jamanetwork.com
Importance An increased risk of lymphoma has been reported among patients receiving
thiopurines for inflammatory bowel disease (IBD). The risk of lymphoma associated with anti …

Market share and costs of biologic therapies for inflammatory bowel disease in the USA

H Yu, D MacIsaac, JJ Wong, ZM Sellers… - Alimentary …, 2018 - Wiley Online Library
Background Real‐world data quantifying the costs of increasing use of biologics in
inflammatory bowel disease (IBD) are unknown. Aim To determine the outpatient IBD drug …

The effectiveness of either ustekinumab or vedolizumab in 239 patients with Crohn's disease refractory to anti‐tumour necrosis factor

H Alric, A Amiot, J Kirchgesner, X Tréton… - Alimentary …, 2020 - Wiley Online Library
Background There is no head‐to‐head trial comparing ustekinumab and vedolizumab in
patients with Crohn's disease (CD) refractory to anti‐tumour necrosis factor (anti‐TNF). Aim …

Increased incidence of systemic serious viral infections in patients with inflammatory bowel disease associates with active disease and use of thiopurines

A Wisniewski, J Kirchgesner, P Seksik… - United European …, 2020 - journals.sagepub.com
Background The magnitude and drivers of the risk of serious viral infections in Inflammatory
Bowel diseases (IBD) are unclear. Objective The objective of this study was to assess the …

Increased risk of acute arterial events in young patients and severely active IBD: a nationwide French cohort study

J Kirchgesner, L Beaugerie, F Carrat, NN Andersen… - Gut, 2018 - gut.bmj.com
Objective Magnitude and independent drivers of the risk of acute arterial events in IBD are
still unclear. We addressed this question in patients with IBD compared with the general …

Combined biologic and immunomodulatory therapy is superior to monotherapy for decreasing the risk of inflammatory bowel disease-related complications

LE Targownik, EI Benchimol… - Journal of Crohn's …, 2020 - academic.oup.com
Abstract Background and Aims The combination of infliximab and azathioprine is more
efficacious than either therapy alone for Crohn's disease [CD] and ulcerative colitis [UC] …

Epidemiological, clinical, patient-reported and economic burden of inflammatory bowel disease (ulcerative colitis and crohn's disease) in Spain: a systematic review

M Barreiro-de Acosta, A Molero, E Artime… - Advances in …, 2023 - Springer
Introduction This study describes the epidemiological, clinical, patient-reported and
economic burden of inflammatory bowel disease (IBD), including Crohn's disease (CD) and …