Poly (glycolic acid)(PGA): A versatile building block expanding high performance and sustainable bioplastic applications

PK Samantaray, A Little, DM Haddleton, T McNally… - Green …, 2020 - pubs.rsc.org
The concerns about the accumulating plastic waste pollution have stimulated the rapid
development of bioplastics, in particular biodegradable bioplastics derived from renewable …

Curcumin encapsulation in functional PLGA nanoparticles: A promising strategy for cancer therapies

F da Silva Feltrin, T Agner, C Sayer… - Advances in colloid and …, 2022 - Elsevier
Nanoparticles have emerged as promising drug delivery systems for the treatment of several
diseases. Novel cancer therapies have exploited these particles as alternative adjuvant …

Long-acting PLGA microspheres: advances in excipient and product analysis toward improved product understanding

B Wan, Q Bao, D Burgess - Advanced drug delivery reviews, 2023 - Elsevier
Poly (lactic-co-glycolic acid)(PLGA) microspheres are a sustained-release drug delivery
system with several successful commercial products used for the treatment of a variety of …

Biodegradable implants for sustained drug release in the eye

SS Lee, P Hughes, AD Ross, MR Robinson - Pharmaceutical research, 2010 - Springer
The safety and effectiveness of systemic and topical medical therapies for ocular disorders
are limited due to poor ocular drug uptake, nonspecificity to target tissues, systemic side …

Topical sustained drug delivery to the retina with a drug-eluting contact lens

AE Ross, LC Bengani, R Tulsan, DE Maidana… - Biomaterials, 2019 - Elsevier
Intravitreal injections and implants are used to deliver drugs to the retina because
therapeutic levels of these medications cannot be provided by topical administration (ie eye …

Recent advances in PLGA based nanocarriers for drug delivery system: a state of the art review

SR Pardeshi, A Nikam, P Chandak… - … Journal of Polymeric …, 2023 - Taylor & Francis
The biomolecules in the clinical use being delivered by the conventional mode of delivery
often exhibit poor affinity. So, there is a need for a nanomedicine-based approach that could …

Engineering and polymeric composition of drug‐eluting suture: a review

X Deng, M Qasim, A Ali - Journal of Biomedical Materials …, 2021 - Wiley Online Library
Sutures are the most popular surgical implants in the global surgical equipment market.
They are used for holding tissues together to achieve wound closure. However, controlling …

Reverse engineering the Ozurdex dexamethasone intravitreal implant

MA Costello, J Liu, Y Wang, B Qin, X Xu, Q Li… - International Journal of …, 2023 - Elsevier
Ozurdex is a biodegradable implant formulated for sustained-release delivery of the
corticosteroid dexamethasone to the posterior segment of the eye. The small, rod-shaped …

[HTML][HTML] Recent Applications of PLGA in Drug Delivery Systems

J Yang, H Zeng, Y Luo, Y Chen, M Wang, C Wu… - …, 2024 - pmc.ncbi.nlm.nih.gov
Poly (lactic-co-glycolic acid)(PLGA) is a widely used biodegradable and biocompatible
copolymer in drug delivery systems (DDSs). In this article, we highlight the critical …

Drug release mechanisms of high-drug-load, melt-extruded dexamethasone intravitreal implants

MA Costello, J Liu, B Chen, Y Wang, B Qin, X Xu… - European Journal of …, 2023 - Elsevier
Ozurdex is an FDA–approved sustained-release, biodegradable implant formulated to
deliver the corticosteroid dexamethasone to the posterior segment of the eye for up to 6 …