Current understanding of the molecular mechanisms in Parkinson's disease: Targets for potential treatments

P Maiti, J Manna, GL Dunbar - Translational neurodegeneration, 2017 - Springer
Gradual degeneration and loss of dopaminergic neurons in the substantia nigra, pars
compacta and subsequent reduction of dopamine levels in striatum are associated with …

Obesity and aging: Molecular mechanisms and therapeutic approaches

AL Santos, S Sinha - Ageing Research Reviews, 2021 - Elsevier
The epidemic of obesity is a major challenge for health policymakers due to its far-reaching
effects on population health and potentially overwhelming financial burden on healthcare …

Polyphenols in Parkinson's disease: a systematic review of in vivo studies

M Kujawska, J Jodynis-Liebert - Nutrients, 2018 - mdpi.com
Parkinson's disease (PD) is the second most common neurodegenerative disorder.
However, therapeutic options treating only its symptoms are very disappointing. Therefore …

[HTML][HTML] The emerging role of nutrition in Parkinson's disease

SE Seidl, JA Santiago, H Bilyk… - Frontiers in aging …, 2014 - frontiersin.org
Typically, Parkinson's disease (PD) is the second most prevalent neurodegenerative
disease in ageing individuals. It is now clear that genetic susceptibility and environmental …

Fermented soy products: Beneficial potential in neurodegenerative diseases

CH Jang, J Oh, JS Lim, HJ Kim, JS Kim - Foods, 2021 - mdpi.com
Fermented soybean products, such as cheonggukjang (Japanese natto), doenjang (soy
paste), ganjang (soy sauce), and douchi, are widely consumed in East Asian countries and …

Control of reactive oxygen species for the prevention of Parkinson's disease: the possible application of flavonoids

TY Kim, E Leem, JM Lee, SR Kim - Antioxidants, 2020 - mdpi.com
Oxidative stress reflects an imbalance between the production of reactive oxygen species
(ROS) and antioxidant defense systems, and it can be associated with the pathogenesis and …

Genistein ameliorates learning and memory deficits in amyloid β (1–40) rat model of Alzheimer's disease

M Bagheri, MT Joghataei, S Mohseni… - Neurobiology of Learning …, 2011 - Elsevier
Alzheimer's disease (AD) is a debilitating neurodegenerative disorder characterized by
increased β-amyloid (Aβ) deposition and neuronal dysfunction leading to impaired learning …

Sex differences in Parkinson's disease and other movement disorders

KM Smith, N Dahodwala - Experimental neurology, 2014 - Elsevier
Movement disorders including Parkinson's disease (PD), Huntington's disease (HD), chorea,
tics, and Tourette's syndrome (TS) display sex differences in disease susceptibility, disease …

Neuroactive steroids and Parkinson's disease: Review of human and animal studies

M Bourque, M Morissette, T Di Paolo - Neuroscience & Biobehavioral …, 2024 - Elsevier
The greater prevalence and incidence of Parkinson's disease (PD) in men suggest a
beneficial effect of sex hormones. Neuroactive steroids have neuroprotective activities thus …

Isoflavones derived from plant raw materials: Bioavailability, anti-cancer, anti-aging potentials, and microbiome modulation

SA Aboushanab, SM Khedr, IF Gette… - Critical Reviews in …, 2022 - Taylor & Francis
Isoflavones are secondary metabolites that represent the most abundant category of plant
polyphenols. Dietary soy, kudzu, and red clover contain primarily genistein, daidzein …