The second international consensus guidelines on the management of BK polyomavirus in kidney transplantation

CN Kotton, N Kamar, D Wojciechowski, M Eder… - …, 2024 - journals.lww.com
BK polyomavirus (BKPyV) remains a significant challenge after kidney transplantation.
International experts reviewed current evidence and updated recommendations according …

BK virus nephropathy in kidney transplantation: a state-of-the-art review

S Kant, A Dasgupta, S Bagnasco, DC Brennan - Viruses, 2022 - mdpi.com
BK virus maintains a latent infection that is ubiquitous in humans. It has a propensity for
reactivation in the setting of a dysfunctional cellular immune response and is frequently …

BK polyomavirus in solid organ transplantation—Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice

HH Hirsch, PS Randhawa… - Clinical …, 2019 - Wiley Online Library
The present AST‐IDCOP guidelines update information on BK polyomavirus (BKP yV)
infection, replication, and disease, which impact kidney transplantation (KT), but rarely non …

BK polyomavirus nephropathy in kidney transplantation: balancing rejection and infection

CL Shen, BS Wu, TJ Lien, AH Yang, CY Yang - Viruses, 2021 - mdpi.com
BK polyomavirus nephropathy (BKVN) and allograft rejection are two closely-associated
diseases on opposite ends of the immune scale in kidney transplant recipients. The principle …

Neutralizing antibody–mediated response and risk of BK virus–associated nephropathy

M Solis, A Velay, R Porcher… - Journal of the …, 2018 - journals.lww.com
BK virus–associated nephropathy (BKVAN) causes renal allograft dysfunction. The current
management of BKVAN relies on pre-emptive adaptation of immunosuppression according …

[HTML][HTML] Role of novel biomarkers in kidney transplantation

KJ Swanson, F Aziz, N Garg, M Mohamed… - World journal of …, 2020 - ncbi.nlm.nih.gov
Clinical application of biomarkers is an integral component of transplant care. Clinicians and
scientists alike are in search of better biomarkers than the current serologic (serum …

Human memory B cells harbor diverse cross-neutralizing antibodies against BK and JC polyomaviruses

JM Lindner, V Cornacchione, A Sathe, C Be, H Srinivas… - Immunity, 2019 - cell.com
Human polyomaviruses cause a common childhood infection worldwide and typically elicit a
neutralizing antibody and cellular immune response, while establishing a dormant infection …

[HTML][HTML] Nonclinical and clinical characterization of MAU868, a novel human-derived monoclonal neutralizing antibody targeting BK polyomavirus VP1

JR Abend, A Sathe, MB Wrobel, M Knapp, L Xu… - American Journal of …, 2024 - Elsevier
Reactivation of BK polyomavirus (BKPyV) can cause significant kidney and bladder disease
in immunocompromised patients. There are currently no effective, BKPyV-specific therapies …

BK polyomavirus-specific antibody and T-cell responses in kidney transplantation: update

A Kaur, M Wilhelm, S Wilk… - Current opinion in …, 2019 - journals.lww.com
BK polyomavirus-specific antibody and T-cell responses in ki... : Current Opinion in Infectious
Diseases BK polyomavirus-specific antibody and T-cell responses in kidney transplantation …

[HTML][HTML] Non-immunological complications following kidney transplantation

A Cohen-Bucay, CE Gordon, JM Francis - F1000Research, 2019 - ncbi.nlm.nih.gov
Kidney transplantation (KT) is the most effective way to decrease the high morbidity and
mortality of patients with end-stage renal disease. However, KT does not completely reverse …