Colonization resistance: the role of gut microbiota in preventing Salmonella invasion and infection

L Deng, S Wang - Gut Microbes, 2024 - Taylor & Francis
The human gastrointestinal tract is colonized by a complex microbial ecosystem, the gut
microbiota, which is pivotal in maintaining host health and mediating resistance to diseases …

Fighting the enemy within: systemic immune defense against mucosal Salmonella infection

AT Nguyen, SJ McSorley - Immunology Letters, 2024 - Elsevier
Salmonella infection remains a persistent global health threat, as different serovars induce a
range of clinical disease, depending upon bacterial virulence and host susceptibility. While …

New insights on an old friend: AroA linked to iron-dependent outer membrane stability

P Chin, CJ Anderson - mBio, 2024 - journals.asm.org
Salmonella is a common causative agent of infectious intestinal and systemic disease and
has been extensively studied for several decades. Yet, much of Salmonella pathogenicity …

成骨细胞条件性视黄酸信号失活小鼠模型的构建与验证

孙思远, 刘媛琪, 崔怡雯, 黄紫晗, 梅李… - 上海交通大学学报 …, 2024 - xuebao.shsmu.edu.cn
目的· 构建并验证可模拟维生素A 缺乏症(vitamin A deficiency, VAD) 导致的颅颌面骨畸形且
出生后可存活的模型小鼠. 方法· 运用Cre-LoxP 重组酶系统, 通过将OsxCre 与Rosa26dnRARα …

Generation and validation of the conditional osteoblast-specific retinoic acid signaling inhibition mouse model

SUN Siyuan, LIU Yuanqi, CUI Yiwen… - Journal of Shanghai …, 2024 - xuebao.shsmu.edu.cn
Objective· To construct and verify the mouse model that can mimic the vitamin A deficiency
(VAD)-like craniofacial skeletal deformity and do not cause embryonic death. Methods …