We report a comprehensive analysis of 412 muscle-invasive bladder cancers characterized
by multiple TCGA analytical platforms. Fifty-eight genes were significantly mutated, and the …

Overtreatment with cisplatin-based chemotherapy is a major issue in the management of
muscle-invasive bladder cancer (MIBC), and currently none of the reported biomarkers for …

Epidemiological data have indicated that there are some sex-related differences in bladder
cancer. Indeed, the incidence of bladder cancer in men has been substantially higher than …

Abstract Background Bladder cancer (BCa) is a frequent urothelial malignancy with a high
ratio of morbidity and mortality. Various genetic and environmental factors are involved in …

Background Solanum nigrum L. decoction has been used as a folklore medicine in China to
prevent the postoperative recurrence of bladder cancer (BC). However, there are no …

Human cancers display a restricted set of expression profiles, despite diverse mutational
drivers. This has led to the hypothesis that select sets of transcription factors act on similar …

Abstract Purpose The combination of Xiaozheng decoction with postoperative intravesical
instillation has been shown to improve the prognosis of bladder cancer patients and prevent …

Background Bladder cancer (BCa) is a common urological malignant tumor worldwide, and
recurrence and death still remain high. New therapeutic targets are needed to treat patients …

Enhancers are transcriptional regulatory elements that increase target gene expression. It
has reported that enhancers could universally transcribe into enhancer RNAs (eRNAs) with …

Anilin actin binding protein (ANLN) and transducing-like enhancer protein 2 (TLE2) are
associated with cancer patient survival and progression. The impact of their gene …