Design of NIR-II high performance organic small molecule fluorescent probes and summary of their biomedical applications

X Liu, B Yu, Y Shen, H Cong - Coordination Chemistry Reviews, 2022 - Elsevier
Near-infrared fluorescence imaging has gained a lot of attention in biomedicine by virtue of
its high sensitivity, high specificity, and many other advantages. Moreover, near-infrared II …

Photo‐facilitated chemodynamic therapeutic agents: Synthesis, mechanisms, and biomedical applications

N Yang, C Cao, X Lv, T Zhang, J Shao, X Song… - …, 2023 - Wiley Online Library
Chemodynamic therapy (CDT) utilizes Fenton and/or Fenton‐like reactions in the tumor
microenvironment (TME) to produce cytotoxic reactive oxygen species (ROS, mainly …

A versatile metal–organic nanoplatform in combination with CXCR4 antagonist and PD-L1 inhibitor for multimodal synergistic cancer therapy and MRI-guided tumor …

D Liu, H He, F Kong, Y Cao, F Zang, M Ma, N Gu… - Nano Today, 2022 - Elsevier
Currently, multimodal synergistic nanoplatform emerges as an important cancer therapy
paradigm, however, multimodal synergistic theranostic nanoplatform remains to be …

Three Strategies in Engineering Nanomedicines for Tumor Microenvironment‐Enabled Phototherapy

S He, X Jia, S Feng, J Hu - Small, 2023 - Wiley Online Library
Canonical phototherapeutics have several limitations, including a lack of tumor selectivity,
nondiscriminatory phototoxicity, and tumor hypoxia aggravation. The tumor …

Tumor microenvironment responsive theranostic agent for enhanced chemo/chemodynamic/photothermal therapy

J Wang, W Kong, H Jin, C Li, Q Luo, Y Luo… - Colloids and Surfaces B …, 2022 - Elsevier
The specific characteristics of the tumor microenvironment (TME) and monotherapy always
lead to poor therapy effects for tumors. Hereby, we have developed a smart multifunctional …

New insight into the application of fluorescence platforms in tumor diagnosis: From chemical basis to clinical application

Y Li, Q Chen, X Pan, W Lu… - Medicinal Research …, 2023 - Wiley Online Library
Early and rapid diagnosis of tumors is essential for clinical treatment or management. In
contrast to conventional means, bioimaging has the potential to accurately locate and …

Multifunctional nanoparticle for cancer therapy

Y Gao, K Wang, J Zhang, X Duan, Q Sun, K Men - MedComm, 2023 - Wiley Online Library
Cancer is a complex disease associated with a combination of abnormal physiological
process and exhibiting dysfunctions in multiple systems. To provide effective treatment and …

ICG-loaded and 125 I-labeled theranostic nanosystem for multimodality imaging-navigated phototherapy of breast cancer

D Wang, J Yue, Q Cao, J Liu, L Yang, W Shen… - Biomaterials …, 2023 - pubs.rsc.org
Multimodality imaging-navigated precise phototherapy has been well-established as a
promising strategy for enhancing the diagnostic and therapeutic efficiency of cancer in …

Copper homeostasis and cuproptosis in central nervous system diseases

Z Zhu, M Song, J Ren, L Liang, G Mao, M Chen - Cell Death & Disease, 2024 - nature.com
Copper (Cu), an indispensable micronutrient for the sustenance of living organisms,
contributes significantly to a vast array of fundamental metabolic processes. The human …

Enzyme-like copper-encapsulating magnetic nanoassemblies for switchable T1-weighted MRI and potentiating chemo-/photo-dynamic therapy

T Li, B Rao, D Xu, J Zhou, W Sun, X Zhi, C Zhang… - Acta biomaterialia, 2022 - Elsevier
Photodynamic therapy (PDT) has become a promising cancer treatment due to in situ
generation of cytotoxic reactive oxygen (ROS); however, it remains limited by the hypoxia of …