Jamming and arrest of cell motion in biological tissues

E Lawson-Keister, ML Manning - Current Opinion in Cell Biology, 2021 - Elsevier
Collective cell motility is crucial to many biological processes including morphogenesis,
wound healing, and cancer invasion. Recently, the biology and biophysics communities …

Active glasses

LMC Janssen - Journal of Physics: Condensed Matter, 2019 - iopscience.iop.org
Active glassy matter has recently emerged as a novel class of non-equilibrium soft matter,
combining energy-driven, active particle movement with dense and disordered glass-like …

Geometric constraints during epithelial jamming

L Atia, D Bi, Y Sharma, JA Mitchel, B Gweon… - Nature physics, 2018 - nature.com
As an injury heals, an embryo develops or a carcinoma spreads, epithelial cells
systematically change their shape. In each of these processes cell shape is studied …

Glassy dynamics in dense systems of active particles

L Berthier, E Flenner, G Szamel - The Journal of chemical physics, 2019 - pubs.aip.org
Despite the diversity of materials designated as active matter, virtually all active systems
undergo a form of dynamic arrest when crowding and activity compete, reminiscent of the …

A minimal-length approach unifies rigidity in underconstrained materials

M Merkel, K Baumgarten, BP Tighe… - Proceedings of the …, 2019 - National Acad Sciences
We present an approach to understand geometric-incompatibility–induced rigidity in
underconstrained materials, including subisostatic 2D spring networks and 2D and 3D …

Cell cycle dynamics control fluidity of the developing mouse neuroepithelium

L Bocanegra-Moreno, A Singh, E Hannezo… - Nature Physics, 2023 - nature.com
As developing tissues grow in size and undergo morphogenetic changes, their material
properties may be altered. Such changes result from tension dynamics at cell contacts or …

Finding defects in glasses through machine learning

S Ciarella, D Khomenko, L Berthier, FC Mocanu… - Nature …, 2023 - nature.com
Structural defects control the kinetic, thermodynamic and mechanical properties of glasses.
For instance, rare quantum tunneling two-level systems (TLS) govern the physics of glasses …

Cell cycle–dependent active stress drives epithelia remodeling

J Devany, DM Sussman, T Yamamoto… - Proceedings of the …, 2021 - National Acad Sciences
Epithelia have distinct cellular architectures which are established in development,
reestablished after wounding, and maintained during tissue homeostasis despite cell …

Linear viscoelastic properties of the vertex model for epithelial tissues

S Tong, NK Singh, R Sknepnek… - PLoS computational …, 2022 - journals.plos.org
Epithelial tissues act as barriers and, therefore, must repair themselves, respond to
environmental changes and grow without compromising their integrity. Consequently, they …

Understanding, predicting, and tuning the fragility of vitrimeric polymers

S Ciarella, RA Biezemans… - Proceedings of the …, 2019 - National Acad Sciences
Fragility is an empirical property that describes how abruptly a glass-forming material
solidifies upon supercooling. The degree of fragility carries important implications for the …