Zinc fingers and homeoboxes family in human diseases

Y Liu, D Ma, C Ji - Cancer gene therapy, 2015 - nature.com
The zinc-fingers and homeoboxes (ZHX) family is a group of nuclear homodimeric
transcriptional repressors that interact with a subunit of nuclear factor-Y (NF-YA) and contain …

[HTML][HTML] Structural basis of membrane skeleton organization in red blood cells

N Li, S Chen, K Xu, MT He, MQ Dong, QC Zhang… - Cell, 2023 - cell.com
The spectrin-based membrane skeleton is a ubiquitous membrane-associated two-
dimensional cytoskeleton underneath the lipid membrane of metazoan cells. Mutations of …

ZHX2 in health and disease

N Li, Z Wu, C Ma - Frontiers in Oncology, 2022 - frontiersin.org
As a transcriptional factor and the negative regulator of alpha fetal protein (AFP), Zinc fingers
and homeoboxes 2 (ZHX2) has a well-established role in protection against hepatocellular …

ARID1B, a molecular suppressor of erythropoiesis, is essential for the prevention of Monge's disease

P Azad, AB Caldwell, S Ramachandran… - … & molecular medicine, 2022 - nature.com
At high altitude Andean region, hypoxia-induced excessive erythrocytosis (EE) is the
defining feature of Monge's disease or chronic mountain sickness (CMS). At the same …

Interaction between common genetic variants and total fat intake on low-density lipoprotein peak particle diameter: a genome-wide association study

I Rudkowska, L Pérusse, C Bellis, J Blangero… - Lifestyle …, 2015 - karger.com
Abstract Background/Aim: Total fat intake has an important impact on the low-density
lipoprotein (LDL) peak particle diameter (LDL-PPD) and may interact with nutrient-sensitive …

Transcriptome meta-analysis of peripheral lymphomononuclear cells indicates that gestational diabetes is closer to type 1 diabetes than to type 2 diabetes mellitus

CVA Collares, AF Evangelista, DJ Xavier… - Molecular biology …, 2013 - Springer
We performed a meta-analysis of the transcription profiles of type 1, type 2 and gestational
diabetes to evaluate similarities and dissimilarities among these diabetes types. cRNA …

Zhx2 maintains islet β-cell mass and function by transcriptionally regulating Pax6

L Ding, Y Zhang, Y Wang, Y Wang, Z Tong, P Li… - Iscience, 2023 - cell.com
Emerging evidence shows that pancreatic β-cell function and quality are key determinants in
the progression of type 2 diabetes (T2D). The transcription factor zinc finger homeobox 2 …

[HTML][HTML] SH3BGRL2 exerts a dual function in breast cancer growth and metastasis and is regulated by TGF-β1

DD Li, L Deng, SY Hu, FL Zhang… - American journal of cancer …, 2020 - ncbi.nlm.nih.gov
SH3 domain-binding glutamic acid-rich-like protein 2 (SH3BGRL2) is a poorly defined
member of the SH3BGR gene family with potential roles in cell differentiation and tissue …

Proliferation and osteo/odontogenic differentiation of stem cells from apical papilla regulated by Zinc fingers and homeoboxes 2: An in vitro study

F Wan, L Gao, Y Lu, H Ma, H Wang, X Liang… - Biochemical and …, 2016 - Elsevier
In the process of tooth root development, stem cells from the apical papilla (SCAPs) can
differentiate into odontoblasts and form root dentin, however, molecules regulating SCAPs …

Novel Regulation of the Transcription Factor ZHX2 by Nα-Modification

MM Conner - 2023 - search.proquest.com
Protein N-terminal (Nα) modifications, occurring both co-and post-translationally on the α-
amino group at the N-terminus of proteins, regulate many aspects of protein biochemistry …