[HTML][HTML] The importance of poly (ethylene glycol) alternatives for overcoming PEG immunogenicity in drug delivery and bioconjugation

TT Hoang Thi, EH Pilkington, DH Nguyen, JS Lee… - Polymers, 2020 - mdpi.com
Poly (ethylene glycol)(PEG) is widely used as a gold standard in bioconjugation and
nanomedicine to prolong blood circulation time and improve drug efficacy. The conjugation …

[HTML][HTML] Advances in nanomaterial-based targeted drug delivery systems

X Cheng, Q Xie, Y Sun - Frontiers in bioengineering and …, 2023 - frontiersin.org
Nanomaterial-based drug delivery systems (NBDDS) are widely used to improve the safety
and therapeutic efficacy of encapsulated drugs due to their unique physicochemical and …

Nanodiscs: a versatile nanocarrier platform for cancer diagnosis and treatment

J Bariwal, H Ma, GA Altenberg, H Liang - Chemical Society Reviews, 2022 - pubs.rsc.org
Cancer therapy is a significant challenge due to insufficient drug delivery to the cancer cells
and non-selective killing of healthy cells by most chemotherapy agents. Nano-formulations …

[HTML][HTML] Tailoring polymer dispersity and shape of molecular weight distributions: methods and applications

R Whitfield, NP Truong, D Messmer, K Parkatzidis… - Chemical …, 2019 - pubs.rsc.org
The width and shape of molecular weight distributions can significantly affect the properties
of polymeric materials and thus are key parameters to control. This mini-review aims to …

[HTML][HTML] Advances in drug delivery to atherosclerosis: Investigating the efficiency of different nanomaterials employed for different type of drugs

B Perera, Y Wu, NT Nguyen, HT Ta - Materials Today Bio, 2023 - Elsevier
Atherosclerosis is the build-up of fatty deposits in the arteries. Atherosclerosis is the main
underlying cause of cardiovascular diseases and the leading cause of global morbidity and …

Effect of micro-and nanoparticle shape on biological processes

H Hadji, K Bouchemal - Journal of Controlled Release, 2022 - Elsevier
In the drug delivery field, there is beyond doubt that the shape of micro-and nanoparticles
(M&NPs) critically affects their biological fate. Herein, following an introduction describing …

Controlling nanomaterial size and shape for biomedical applications via polymerization‐induced self‐assembly

SY Khor, JF Quinn, MR Whittaker… - Macromolecular …, 2019 - Wiley Online Library
Rapid developments in the polymerization‐induced self‐assembly (PISA) technique have
paved the way for the environmentally friendly production of nanoparticles with tunable size …

Non-spherical micro-and nanoparticles in nanomedicine

X Zhu, C Vo, M Taylor, BR Smith - Materials Horizons, 2019 - pubs.rsc.org
Recent studies have revealed the effects of shape on in vivo nanoparticle circulation,
distribution, extravasation, and cellular uptake. Morphology is therefore becoming a key …

Molecular sensors of blood flow in endothelial cells

S Baratchi, K Khoshmanesh, OL Woodman… - Trends in molecular …, 2017 - cell.com
Mechanical stress from blood flow has a significant effect on endothelial physiology, with a
key role in initiating vasoregulatory signals. Disturbances in blood flow, such as in regions of …

A Spiky Silver‐Iron Oxide Nanoparticle for Highly Efficient Targeted Photothermal Therapy and Multimodal Imaging of Thrombosis

KX Vazquez‐Prada, SS Moonshi, Y Wu, F Akther… - Small, 2023 - Wiley Online Library
Thrombosis and its complications are responsible for 30% of annual deaths. Limitations of
methods for diagnosing and treating thrombosis highlight the need for improvements …