The recent epidemics of metabolic diseases, obesity, type 2 diabetes (T2D), liver lipid
disorders and metabolic syndrome have largely been attributed to genetic background and …

In 1997, the first in vivo bisphenol A (BPA) study by endocrinologists reported that feeding
BPA to pregnant mice induced adverse reproductive effects in male offspring at the low dose …

For decades, studies of endocrine-disrupting chemicals (EDCs) have challenged traditional
concepts in toxicology, in particular the dogma of “the dose makes the poison,” because …

Non-monotonic dose response curves (NMDRCs) have been demonstrated for natural
hormones and endocrine disrupting chemicals (EDCs) in a variety of biological systems …

Five years ago, an ambitious collaboration, the Consortium Linking Academic and
Regulatory Insights on Toxicity of BPA (CLARITY–BPA; henceforth CLARITY), was launched …

Rats have long been recognized as a valuable biomedical research model, notably in the
investigation of aging, toxicology, addiction, and common human diseases such as diabetes …

Incidences of altered development and neoplasia of male reproductive organs have
increased during the last 50 years, as shown by epidemiological data. These data are …

Since its initial sales in the 1970s, the herbicide glyphosate attained widespread use in
modern agriculture, becoming the most commercially successful and widely used herbicide …

For years, scientists from various disciplines have studied the effects of endocrine disrupting
chemicals (EDCs) on the health and wellbeing of humans and wildlife. Some studies have …

There is extensive evidence that bisphenol A (BPA) is related to a wide range of adverse
health effects based on both human and experimental animal studies. However, a number of …