Gliomas are the common type of brain tumors originating from glial cells. Epidemiologically,
gliomas occur among all ages, more often seen in adults, which males are more susceptible …

Background Brain cancer is a destructive and life-threatening disease that imposes
immense negative effects on patients' lives. Therefore, the detection of brain tumors at an …

Transforming growth factor β (TGF-β) has long been identified with its intensive involvement
in early embryonic development and organogenesis, immune supervision, tissue repair, and …

Effective drug delivery and prevention of postoperative recurrence are significant challenges
for current glioblastoma (GBM) treatment. Poor drug delivery is mainly due to the presence …

• Early symptoms of brain tumours in adults are non-specific, and patients may present
multiple times to primary care services before they are referred for investigation. Look for …

Background Copper ions are essential for cellular physiology. Cuproptosis is a novel
method of copper-dependent cell death, and the cuproptosis-based signature for glioma …

Exosomes are emerging as important elements that participate in intercellular
communication and tumor microenvironment modulation, but the exact mechanisms by …

Exosomes participate in intercellular communication and glioma microenvironment
modulation, but the exact mechanisms by which glioma-derived exosomes (GDEs) promote …

In patients with glioblastoma, resistance to the chemotherapeutic temozolomide (TMZ) limits
any survival benefits conferred by the drug. Here we show that the convection-enhanced …

The chemical modification of RNA is a newly discovered epigenetic regulation mechanism
in cells and plays a crucial role in a variety of biological processes. N6-methyladenine (m6A) …