LungTech, an EORTC Phase II trial of stereotactic body radiotherapy for centrally located lung tumours: a clinical perspective

S Adebahr, S Collette, E Shash… - The British journal of …, 2015 - academic.oup.com
Evidence supports stereotactic body radiotherapy (SBRT) as a curative treatment option for
inoperable early stage non-small-cell lung cancer (NSCLC) resulting in high rates of tumour …

Effect of chemoradiotherapy vs chemotherapy on survival in patients with locally advanced pancreatic cancer controlled after 4 months of gemcitabine with or without …

P Hammel, F Huguet, JL van Laethem, D Goldstein… - Jama, 2016 - jamanetwork.com
Importance In locally advanced pancreatic cancer, the role of chemoradiotherapy is
controversial and the efficacy of erlotinib is unknown. Objectives To assess whether …

Radiotherapy dosimetry audit: three decades of improving standards and accuracy in UK clinical practice and trials

CH Clark, EGA Aird, S Bolton, EA Miles… - The British journal of …, 2015 - academic.oup.com
Dosimetry audit plays an important role in the development and safety of radiotherapy.
National and large scale audits are able to set, maintain and improve standards, as well as …

PEACE V–Salvage Treatment of OligoRecurrent nodal prostate cancer Metastases (STORM): A study protocol for a randomized controlled phase II trial

A De Bruycker, A Spiessens, P Dirix, N Koutsouvelis… - BMC cancer, 2020 - Springer
Background Pelvic nodal recurrences are being increasingly diagnosed with the
introduction of new molecular imaging techniques, like choline and PSMA PET-CT, in the …

[HTML][HTML] QUARTET: a SIOP Europe project for quality and excellence in radiotherapy and imaging for children and adolescents with cancer

SM Kelly, R Effeney, MN Gaze… - European Journal of …, 2022 - Elsevier
Abstract The European Society for Paediatric Oncology (SIOPE) Radiation Oncology
Working Group presents the QUARTET Project: a centralised quality assurance programme …

[HTML][HTML] Development and evaluation of an online three-level proton vs photon decision support prototype for head and neck cancer–comparison of dose, toxicity and …

Q Cheng, E Roelofs, BLT Ramaekers, D Eekers… - Radiotherapy and …, 2016 - Elsevier
To quantitatively assess the effectiveness of proton therapy for individual patients, we
developed a prototype for an online platform for proton decision support (PRODECIS) …

[HTML][HTML] IDEAL-CRT: a phase 1/2 trial of isotoxic dose-escalated radiation therapy and concurrent chemotherapy in patients with stage II/III non-small cell lung cancer

DB Landau, L Hughes, A Baker, AT Bates… - International Journal of …, 2016 - Elsevier
Purpose To report toxicity and early survival data for IDEAL-CRT, a trial of dose-escalated
concurrent chemoradiotherapy (CRT) for non-small cell lung cancer. Patients and Methods …

Impact of deviations in target volume delineation–time for a new RTQA approach?

S Cox, A Cleves, E Clementel, E Miles… - Radiotherapy and …, 2019 - Elsevier
The international radiotherapy community has recognised that non-adherence to RT
protocols can influence trial endpoints. However this conclusion is based on studies …

The radiotherapy quality assurance gap among phase III cancer clinical trials

KL Corrigan, S Kry, RM Howell, R Kouzy… - Radiotherapy and …, 2022 - Elsevier
Purpose Quality assurance (QA) practices improve the quality level of oncology trials by
ensuring that the protocol is followed and the results are valid and reproducible. This study …

[HTML][HTML] From multisource data to clinical decision aids in radiation oncology: the need for a clinical data science community

J Kazmierska, A Hope, E Spezi, S Beddar… - Radiotherapy and …, 2020 - Elsevier
Big data are no longer an obstacle; now, by using artificial intelligence (AI), previously
undiscovered knowledge can be found in massive data collections. The radiation oncology …