Molecular mechanisms in autoimmune thyroid disease

H Vargas-Uricoechea - Cells, 2023 - mdpi.com
The most common cause of acquired thyroid dysfunction is autoimmune thyroid disease,
which is an organ-specific autoimmune disease with two presentation phenotypes …

The emerging role of exosomes in innate immunity, diagnosis and therapy

P Gangadaran, H Madhyastha, R Madhyastha… - Frontiers in …, 2023 - frontiersin.org
Exosomes, which are nano-sized transport bio-vehicles, play a pivotal role in maintaining
homeostasis by exchanging genetic or metabolic information between different cells …

Association of thyroid dysfunction with suicide attempts in first-episode and drug naïve patients with major depressive disorder

Y Shen, F Wu, Y Zhou, Y Ma, X Huang, Y Ning… - Journal of affective …, 2019 - Elsevier
Backgrounds Thyroid dysfunction was reported to be associated with depression; however,
its role in suicide risk in patients with major depressive disorder (MDD) remains unclear. The …

Thyroid peroxidase as a dual active site enzyme: Focus on biosynthesis, hormonogenesis and thyroid disorders of autoimmunity and cancer

M Godlewska, PJ Banga - Biochimie, 2019 - Elsevier
Thyroid peroxidase (TPO) is the key enzyme involved in thyroid hormone synthesis.
Autoantibodies to TPO (TPOAbs) are a hallmark of autoimmune thyroid disease (AITD) …

Genetic susceptibility to joint occurrence of polycystic ovary syndrome and Hashimoto's thyroiditis: how far is our understanding?

N Zeber-Lubecka, EE Hennig - Frontiers in immunology, 2021 - frontiersin.org
Polycystic ovary syndrome (PCOS) and Hashimoto's thyroiditis (HT) are endocrine disorders
that commonly occur among young women. A higher prevalence of HT in women with …

Meta‐analysis of the association between vitamin D receptor polymorphisms and the risk of autoimmune thyroid disease

XR Gao, YG Yu - International journal of endocrinology, 2018 - Wiley Online Library
The association between vitamin D receptor (VDR) polymorphisms (rs731236, rs1544410,
rs2228570, and rs7975232) and the risk of autoimmune thyroid disease (AITD) had been …

Thyroglobulin antibodies are associated with symptom burden in patients with Hashimoto's thyroiditis: a cross-sectional study

A Barić, L Brčić, S Gračan, V Škrabić… - Immunological …, 2019 - Taylor & Francis
Background: Hashimoto's thyroiditis (HT) is the most common form of autoimmune thyroid
disorders characterized by lower production of thyroid hormones and positivity to …

Are thyroid autoimmune diseases associated with cardiometabolic risks in a population with normal thyroid‐stimulating hormone?

Y Chen, C Zhu, Y Chen, N Wang, Q Li… - Mediators of …, 2018 - Wiley Online Library
Background. The interrelation between thyroid autoimmunity and cardiovascular risks is
complex and has not been confirmed. This study aimed at evaluating whether there exists a …

A higher ratio of estradiol to testosterone is associated with autoimmune thyroid disease in males

Y Chen, Y Chen, F Xia, N Wang, C Chen, X Nie, Q Li… - Thyroid, 2017 - liebertpub.com
Background: Autoimmune thyroid disease (AITD) is highly prevalent. Although AITD is less
common in males, it is unclear whether estradiol (E2) combined with total testosterone (T) …

Association of Phthalate exposure with thyroid function and thyroid homeostasis parameters in type 2 diabetes

Y Chen, W Zhang, JS Chen, N Wang… - Journal of diabetes …, 2021 - Wiley Online Library
Aims. Phthalates, which are recognized environmental endocrine‐disrupting chemicals, are
associated with thyroid hormone disruption. We aimed to evaluate the relationship of …