N6-methyladenosine modification of HCV RNA genome regulates cap-independent IRES-mediated translation via YTHDC2 recognition
GW Kim, A Siddiqui - … of the National Academy of Sciences, 2021 - National Acad Sciences
Hepatitis C virus (HCV) infections are associated with the risk of progression to fibrosis,
cirrhosis, and hepatocellular carcinoma. The HCV RNA genome is translated by an internal …
cirrhosis, and hepatocellular carcinoma. The HCV RNA genome is translated by an internal …
N6-methyladenosine modification of the 5′ epsilon structure of the HBV pregenome RNA regulates its encapsidation by the viral core protein
GW Kim, JS Moon, A Siddiqui - Proceedings of the National …, 2022 - National Acad Sciences
Hepatitis B virus (HBV) contains a partially double-stranded DNA genome. During infection,
its replication is mediated by reverse transcription (RT) of an RNA intermediate termed …
its replication is mediated by reverse transcription (RT) of an RNA intermediate termed …
Next-generation sequencing: A new avenue to understand viral RNA–protein interactions
The genomes of RNA viruses present an astonishing source of both sequence and structural
diversity. From intracellular viral RNA-host interfaces to interactions between the RNA …
diversity. From intracellular viral RNA-host interfaces to interactions between the RNA …
Ribonomics approaches to identify RBPome in plants and other eukaryotes: current progress and future prospects
RNA-binding proteins (RBPs) form complex interactions with RNA to regulate the cell's
activities including cell development and disease resistance. RNA-binding proteome …
activities including cell development and disease resistance. RNA-binding proteome …
Hepatitis B virus X protein expression is tightly regulated by N6-methyladenosine modification of its mRNA
GW Kim, A Siddiqui - Journal of Virology, 2022 - Am Soc Microbiol
Hepatitis B virus (HBV) encodes a regulatory protein, termed HBx, that has been intensely
studied in the past and shown to play a key role (s) in viral transcription and replication. In …
studied in the past and shown to play a key role (s) in viral transcription and replication. In …
Removal of Pseudomonas type IV pili by a small RNA virus
The retractile type IV pilus (T4P) is important for virulence of the opportunistic human
pathogen Pseudomonas aeruginosa. The single-stranded RNA (ssRNA) phage PP7 binds …
pathogen Pseudomonas aeruginosa. The single-stranded RNA (ssRNA) phage PP7 binds …
New insights into mitochondrial–nuclear interactions revealed through analysis of small RNAs
A Pozzi, DK Dowling - Genome biology and evolution, 2022 - academic.oup.com
Mitochondrial sequence variants affect phenotypic function, often through interaction with
the nuclear genome. These “mitonuclear” interactions have been linked both to evolutionary …
the nuclear genome. These “mitonuclear” interactions have been linked both to evolutionary …
N6-Methyladenine Modification of Hepatitis Delta Virus Regulates Its Virion Assembly by Recruiting YTHDF1
Hepatitis delta virus (HDV) is a defective satellite virus that uses hepatitis B virus (HBV)
envelope proteins to form its virions and infect hepatocytes via the HBV receptors …
envelope proteins to form its virions and infect hepatocytes via the HBV receptors …
Footprinting SHAPE-eCLIP reveals transcriptome-wide hydrogen bonds at RNA-protein interfaces
Discovering the interaction mechanism and location of RNA-binding proteins (RBPs) on
RNA is critical for understanding gene expression regulation. Here, we apply selective 2 …
RNA is critical for understanding gene expression regulation. Here, we apply selective 2 …
Modeling the structure and DAP5-binding site of the FGF-9 5′-UTR RNA utilized in cap-independent translation
A Whittaker, DJ Goss - RNA, 2024 - rnajournal.cshlp.org
Cap-independent or eukaryotic initiation factor (eIF) 4E-independent, translation initiation in
eukaryotes requires scaffolding protein eIF4G or its homolog, death-associated protein 5 …
eukaryotes requires scaffolding protein eIF4G or its homolog, death-associated protein 5 …