Gene expression in cells is determined by the epigenetic state of chromatin. Therefore, the
study of epigenetic changes is very important to understand the regulatory mechanism of …

Background Mature sperm carry thousands of RNAs, including mRNAs, lncRNAs, tRNAs,
rRNAs and sncRNAs, though their functional significance is still a matter of debate. Growing …

PIWI proteins and PIWI-interacting RNAs (piRNAs) suppress transposon activity in animals,
thus protecting their genomes from detrimental insertion mutagenesis. Here, we reveal that …

Small non-coding RNAs have been linked to different phenotypes in bovine sperm, however
attempts to identify sperm-borne molecular biomarkers of male fertility have thus far failed to …

Background During epididymal transit, spermatozoa go through several functional
maturation steps, resulting from interactions with epididymal secretomes specific to each …

Hiding in plain sight within the genome of virtually every eukaryotic organism are large
numbers of sequences known as transposable elements (TEs). These sequences often …

Small noncoding RNAs (sncRNAs) are key regulators of the majority of human reproduction
events. Understanding their function in the context of gametogenesis and embryogenesis …

Embryo implantation depends on two primary factors: the quality of the embryo and
endometrial receptivity. Small RNAs have been shown to be potent epigenetic regulators …

In mammals, small non-coding RNAs (sncRNAs) have been reported to be important during
early embryo development. However, a comprehensive assessment of the inventory of …

Background Spermatogenesis is a cellular differentiation process that includes three major
events: mitosis of spermatogonia, meiosis of spermatocytes and spermiogenesis. Steady …