This review focuses on the regulation of transcription factors, many of which are DNA-
binding proteins that recognize cis-regulatory elements of target genes and are the most …

One of the families of transcription factors implicated in developmental control of gene
expression is that of the POU domain proteins [1–5]. These transcription factors contain a …

The mechanisms of specification of gene expression in a complex tissue such as the brain
remain poorly understood. To provide a model system for the study of gene regulation in a …

Here we report on investigation of the role of the POU domain genes Skin-1a/i (Skn-
1a/i/Epoc/Oct-11) and Testes-1 (Tst-1/Oct-6/SCIP) in epidermis where proliferating basal …

We isolated several clones from a matchmaker two‐hybrid system human lymphocyte cDNA
library using an automodification domain of poly (ADP‐ribose) synthetase (PARS) as a …

Primary transcripts encoding the MADS box superfamily of proteins, such as MEF2 in
animals and ZEMa in plants, are alternatively spliced, producing several isoformic species …

IN eukaryotes, activation of transcription involves an interplay between activators bound to
cis-regulatory elements and factors bound to basal elements near the start site of …

Excess amounts of histones in the cell induce mitotic chromosome loss and genomic
instability, and are therefore detrimental to cell survival. In yeast, excess histones are …

Oct-1 transcription factor has various functions in gene regulation. Its expression level is
increased in several types of cancer and is associated with poor survival prognosis. Here we …

Abstract Oct‐1 and Oct‐2 represent the prototypical example of related transcription factors
with identical DNA recognition properties. They bind functionally critical octamer elements …