Histamine intolerance, also referred to as enteral histaminosis or sensitivity to dietary
histamine, is a disorder associated with an impaired ability to metabolize ingested histamine …

Histamine intolerance (HIT) is assumed to be due to a deficiency of the gastrointestinal (GI)
enzyme diamine oxidase (DAO) and, therefore, the food component histamine not being …

Effective gastrointestinal functionality is crucial in determining animal health, welfare and
performance. A new definition of gastrointestinal functionality has been recently presented …

An underlying cause of histamine intolerance is diamine oxidase (DAO) deficiency, which
leads to defective homeostasis and a higher systemic absorption of histamine. Impaired …

Histamine intolerance (HIT) is a common disorder associated with impaired histamine
metabolism. Notwithstanding, it is often misdiagnosed as other diseases because of its lack …

An intact intestinal barrier is crucial for immune homeostasis and its impairment activates the
immune system and may result in chronic inflammation. The epithelial cells of the intestinal …

Gut health includes normal intestinal physiology, complete intestinal epithelial barrier,
efficient immune response, sustained inflammatory balance, healthy microbiota, high …

A low-histamine diet is currently the most advised strategy to prevent the symptomatology of
histamine intolerance. Conceptually, these diets should be founded on the exclusion of …

In westernized countries, adverse reactions to ingested foods are reported to affect up to
20% of the population. Functional, nonspecific, non-allergic gastrointestinal complaints are …

Nowadays, certain uncertainties related to the onset of histamine adverse effects remain
unsolved and still require further research. Questions still to be resolved include the wide …