[HTML][HTML] Altered mitochondrial function in MASLD: key features and promising therapeutic approaches

T Radosavljevic, M Brankovic, J Samardzic, J Djuretić… - Antioxidants, 2024 - mdpi.com
Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as
nonalcoholic fatty liver disease (NAFLD), encompasses a range of liver conditions from …

[HTML][HTML] A new perspective on liver diseases: focusing on the mitochondria-associated endoplasmic reticulum membranes

M Guo, R Liu, F Zhang, J Qu, Y Yang, X Li - Pharmacological Research, 2024 - Elsevier
The pathogenesis of liver diseases is multifaceted and intricate, posing a persistent global
public health challenge with limited therapeutic options. Therefore, further research into liver …

Green Tea Polyphenol (-)-Epicatechin Pretreatment Mitigates Hepatic Steatosis in an In Vitro MASLD Model

M Hefer, A Petrovic, LK Roguljic… - Current issues in …, 2024 - pmc.ncbi.nlm.nih.gov
Metabolic dysfunction-associated steatotic liver disease (MASLD), previously known as non-
alcoholic fatty liver disease (NAFLD), is becoming more prominent globally due to an …

Polyploidy-mediated resilience in hepatic aging: molecular mechanisms and functional implication

TA Addissouky - Egyptian Liver Journal, 2024 - Springer
Background Polyploidization, a process where cells acquire additional chromosome sets, is
a unique characteristic of hepatocytes. This process has been increasingly recognized as an …

Cyanidin-3-O-glucoside alleviates ethanol-induced liver injury by promoting mitophagy in a Gao-binge mouse model of alcohol-associated liver disease

Q He, Z Yin, Y Chen, Y Wu, D Pan, Y Cui… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Background Alcohol-associated liver disease (ALD) is a leading cause of liver disease-
related deaths worldwide. Unfortunately, approved medications for the treatment of this …

Relevant Aspects of Combined Protocols for Prevention of N (M) AFLD and Other Non‐Communicable Diseases

LA Videla, R Valenzuela… - Molecular Nutrition & …, 2024 - Wiley Online Library
Obesity is a global health issue characterized by the excessive fat accumulation, leading to
an increased risk of chronic noncommunicable diseases (NCDs), including metabolic …

Hepatic Alterations in a BTBR T+ Itpr3tf/J Mouse Model of Autism and Improvement Using Melatonin via Mitigation Oxidative Stress, Inflammation and Ferroptosis

R Rezzani, M Gianò, D Pinto, F Rinaldi… - International Journal of …, 2024 - mdpi.com
Autism spectrum disorder (ASD) is a complicated neurodevelopmental disorder, and its
etiology is not well understood. It is known that genetic and nongenetic factors determine …

Emerging roles of tRNA-derived small RNAs in injuries

M Wang, J Guo, W Chen, H Wang, X Hou - PeerJ, 2024 - peerj.com
Abstract tRNA-derived small RNAs (tsRNAs) are a novel class of small noncoding RNAs,
precisely cleaved from tRNA, functioning as regulatory molecules. The topic of tsRNAs in …

Liquiritin Ameliorates Palmitic Acid‐Induced Hepatic Steatosis in Mouse Primary Hepatocytes by Suppressing the VEGFA Signaling Pathway

Z Qi, W Yan, X Qingfang, Y Lei… - Journal of Food …, 2025 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) has become a global pandemic, imposing a
significant socioeconomic burden. Hepatic steatosis is a key pathological event in NAFLD …

Unveiling the mitophagy puzzle in non-alcoholic fatty liver disease (NAFLD): Six hub genes for early diagnosis and immune modulatory roles

Z Luo, S Yan, Y Chao, M Shen - Heliyon, 2024 - cell.com
Background Non-alcoholic fatty liver disease (NAFLD) stands as a predominant chronic liver
ailment globally, yet its pathogenesis remains elusive. This study aims to identify Hub …