ADHD is a major burden in adulthood, where co-morbid conditions such as depression,
substance use disorder and obesity often dominate the clinical picture. ADHD has …

Major depressive disorder (MDD) is a complex psychiatric disease requiring
multidisciplinary approaches to identify specific risk factors and establish more efficacious …

Major depressive disorder (MDD) is the most common psychiatric disorder and responds for
important psychosocial consequences. Stressful life events, especially early life stress …

The dopamine transporter (DAT) is one of the most relevant and investigated
neurotransmitter transporters. DAT is a plasma membrane protein which plays a …

Many studies have explored the association between n-3 fatty acids and depression, but
research on the associations of n-6 fatty acids and n-6: n-3 ratio with depression is more …

Behavioral genetics studies and new empirical evidence suggest that depression cannot
simply be explained by the influence of single genes but that gene–gene–environment …

Early life stress (ELS) is associated with treatment-resistant depression (TRD), and trauma-
focused psychotherapy benefits TRD patients exposed to ELS. We explored peripheral …

Hyperactivity of the hypothalamic pituitary adrenocortical (HPA) axis is one of the main
clinical findings in depression. The HPA axis is interrelated with glucocorticoid signaling via …

Background Previous studies suggest that alcohol dependence is associated with increased
risk of depression. The occurrence of depressive symptoms is related to polymorphisms in …

Major depressive disorder (MDD) is known to be a highly limiting and disabling disorder
worldwide. The main management for this disorder is based on pharmacological therapy …