Vaccines against Plasmodium vivax: a research challenge
MA Patarroyo, D Calderón… - Expert review of …, 2012 - Taylor & Francis
Malaria caused by Plasmodium vivax continues being a public health problem in tropical
and subtropical areas throughout the whole world. In spite of this species' epidemiological …
and subtropical areas throughout the whole world. In spite of this species' epidemiological …
Increased interleukin-10 and interferon-γ levels in Plasmodium vivax malaria suggest a reciprocal regulation which is not altered by IL-10 gene promoter …
TS Medina, SPT Costa, MD Oliveira, AM Ventura… - Malaria journal, 2011 - Springer
Background In human malaria, the naturally-acquired immune response can result in either
the elimination of the parasite or a persistent response mediated by cytokines that leads to …
the elimination of the parasite or a persistent response mediated by cytokines that leads to …
Host-Parasite Interaction: Selective Pv-fam-a Family Proteins of Plasmodium vivax Bind to a Restricted Number of Human Erythrocyte Receptors
Background. Plasmodium vivax synthesizes the largest number of 36 tryptophan-rich
proteins belonging to the Pv-fam-a family. These parasite proteins need to be characterized …
proteins belonging to the Pv-fam-a family. These parasite proteins need to be characterized …
Erythrocyte Binding Activity Displayed by a Selective Group of Plasmodium vivax Tryptophan Rich Antigens Is Inhibited by Patients' Antibodies
RK Tyagi, YD Sharma - PLoS One, 2012 - journals.plos.org
Plasmodium vivax is a very common but non-cultivable malaria parasite affecting large
human population in tropical world. To develop therapeutic reagents for this malaria, the …
human population in tropical world. To develop therapeutic reagents for this malaria, the …
Presence of Memory T Cells and Naturally Acquired Antibodies in Plasmodium vivax Malaria-Exposed Individuals Against a Group of Tryptophan-Rich Antigens With …
Background. Tryptophan-rich antigens of malarial parasites have been proposed to be the
potential vaccine candidate antigens. Plasmodium vivax contains the largest number of such …
potential vaccine candidate antigens. Plasmodium vivax contains the largest number of such …
Host–parasite interaction: multiple sites in the Plasmodium vivax tryptophan‐rich antigen PvTRAg38 interact with the erythrocyte receptor band 3
Tryptophan‐rich antigens of malarial parasites interact with host molecules and play an
important role in parasite survival. Merozoite expressed Plasmodium vivax tryptophan‐rich …
important role in parasite survival. Merozoite expressed Plasmodium vivax tryptophan‐rich …
CD4+ T Cell Response Correlates with Naturally Acquired Antibodies against Plasmodium vivax Tryptophan-Rich Antigens
M Zeeshan, K Tyagi, YD Sharma - Infection and Immunity, 2015 - Am Soc Microbiol
Tryptophan-rich proteins play important biological functions for the Plasmodium parasite.
Plasmodium vivax contains remarkably large numbers of such proteins belonging to the “Pv …
Plasmodium vivax contains remarkably large numbers of such proteins belonging to the “Pv …
Plasmodium vivax Pv12 B-cell epitopes and HLA-DRβ1*-dependent T-cell epitopes in vitro antigenicity
Malaria is an infectious disease caused by parasites from the genus Plasmodium (P.
falciparum and P. vivax are responsible for 90% of all clinical cases); it is widely distributed …
falciparum and P. vivax are responsible for 90% of all clinical cases); it is widely distributed …
High immunogenecity and erythrocyte-binding activity in the tryptophan-rich domain (TRD) of the 74-kDa Plasmodium vivax alanine-tryptophan-rich antigen …
Plasmodium vivax is the most widespread species of human malaria parasite affecting 70–
80 million people worldwide each year. In recent years, some potential vaccine candidate …
80 million people worldwide each year. In recent years, some potential vaccine candidate …
[HTML][HTML] Plasmodium vivax: immunological properties of tryptophan-rich antigens PvTRAg 35.2 and PvTRAg 80.6
P Mittra, N Singh, YD Sharma - Microbes and infection, 2010 - Elsevier
Need for malaria vaccine necessitates the characterization of potential antigens of the
Plasmodium parasite. Recently, we have identified several Plasmodium vivax tryptophan …
Plasmodium parasite. Recently, we have identified several Plasmodium vivax tryptophan …