Proteomics-Based identification of dysregulated proteins and biomarker discovery in invasive ductal carcinoma, the most common breast cancer subtype
Invasive ductal carcinoma (IDC) is the most common histological subtype of malignant
breast cancer (BC), and accounts for 70–80% of all invasive BCs. IDC demonstrates great …
breast cancer (BC), and accounts for 70–80% of all invasive BCs. IDC demonstrates great …
Matrix metalloproteinases as biomarkers and therapeutic targets in colitis-associated cancer
N Sampaio Moura, A Schledwitz, M Alizadeh… - Frontiers in …, 2024 - frontiersin.org
Colorectal cancer (CRC) remains a major cause of morbidity and mortality. Therapeutic
approaches for advanced CRC are limited and rarely provide long-term benefit. Enzymes …
approaches for advanced CRC are limited and rarely provide long-term benefit. Enzymes …
Fusobacterium nucleatum upregulates MMP7 to promote metastasis-related characteristics of colorectal cancer cell via activating MAPK(JNK)-AP1 axis
S Ou, H Chen, H Wang, J Ye, H Liu, Y Tao… - Journal of translational …, 2023 - Springer
Background Colorectal cancer (CRC) is the third most common malignant tumor.
Fusobacterium nucleatum (F. nucleatum) is overabundant in CRC and associated with …
Fusobacterium nucleatum (F. nucleatum) is overabundant in CRC and associated with …
A microfluidic co-culture model for investigating colonocytes–microbiota interactions in colorectal cancer
D Penarete-Acosta, R Stading, L Emerson, M Horn… - Lab on a Chip, 2024 - pubs.rsc.org
Changes in the abundance of certain bacterial species within the colorectal microbiota
correlate with colorectal cancer (CRC) development. While carcinogenic mechanisms of …
correlate with colorectal cancer (CRC) development. While carcinogenic mechanisms of …
Amaryllidaceae alkaloids decrease the proliferation, invasion, and secretion of clinically relevant cytokines by cultured human colon cancer cells
V Mathieu, B Laguera, M Masi, SA Dulanto… - Biomolecules, 2022 - mdpi.com
Alkaloids isolated from members of the Amaryllidaceae plant family are promising
anticancer agents. The purpose of the current study was to determine if the isocarbostyrils …
anticancer agents. The purpose of the current study was to determine if the isocarbostyrils …
Exploring the role of Fusobacterium nucleatum in colorectal cancer: implications for tumor proliferation and chemoresistance
L Dadgar-Zankbar, Z Elahi, A Shariati… - Cell Communication and …, 2024 - Springer
Fusobacterium nucleatum (Fn) has been extensively studied for its connection to colorectal
cancer (CRC) and its potential role in chemotherapy resistance. Studies indicate that Fn is …
cancer (CRC) and its potential role in chemotherapy resistance. Studies indicate that Fn is …
Spatial profiling of cancer-associated fibroblasts of sporadic early onset colon cancer microenvironment
S Furuhashi, MA Bustos, S Mizuno, S Ryu… - NPJ Precision …, 2023 - nature.com
The incidence of sporadic early-onset colon cancer (EOCC) has increased worldwide. The
molecular mechanisms in the tumor and the tumor microenvironment (TME) in EOCC are not …
molecular mechanisms in the tumor and the tumor microenvironment (TME) in EOCC are not …
Role of matrix metalloproteinases and their inhibitors in locally invasive papillary thyroid cancer
Locally invasive papillary thyroid carcinoma (PTC) protrudes beyond the thyroid capsule
and invades local structures. Matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) …
and invades local structures. Matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) …
Testing sulforaphane as a strategy against toxic chemicals of public health concern by toxicogenomic data analysis: Friend or foe at the gene level–Colorectal …
Abstract Toxic metals (cadmium (Cd), lead (Pb), mercury (Hg) and arsenic (As)) and
plastificators (bis (2–ethylhexyl) phthalate (DEHP), dibutyl phthalate (DBP)) and bisphenol A …
plastificators (bis (2–ethylhexyl) phthalate (DEHP), dibutyl phthalate (DBP)) and bisphenol A …
Nitazoxanide inhibits osteosarcoma cells growth and metastasis by suppressing AKT/mTOR and Wnt/β-catenin signaling pathways
C Ye, M Wei, H Huang, Y Wang, L Zhang… - Biological …, 2022 - degruyter.com
Osteosarcoma (OS) is the most prevalent malignant bone tumor with poor prognosis.
Developing new drugs for the chemotherapy of OS has been a focal point and a major …
Developing new drugs for the chemotherapy of OS has been a focal point and a major …