The surfaces of many bacteria are decorated with long, exquisitely thin appendages called
type IV pili (T4P), dynamic filaments that are rapidly polymerized and depolymerized from a …

SUMMARY Type IV pili (T4P) are multifunctional protein fibers produced on the surfaces of a
wide variety of bacteria and archaea. The major subunit of T4P is the type IV pilin, and …

Prokaryotes have engineered sophisticated surface nanomachines that have allowed them
to colonize Earth and thrive even in extreme environments. Filamentous machineries …

SUMMARY Type IV pili (T4P) are surface-exposed fibers that mediate many functions in
bacteria, including locomotion, adherence to host cells, DNA uptake (competence), and …

Type IV pili (T4P) are ubiquitous in both bacteria and archaea. They are polymers of the
major pilin protein, which has an extended and protruding N-terminal helix, α1, and a …

Neisseria meningitidis use Type IV pili (T4P) to adhere to endothelial cells and breach the
blood brain barrier, causing cause fatal meningitis. T4P are multifunctional polymers of the …

We report here cryoelectron microscopy reconstructions of type IV pili (T4P) from two
important human pathogens, Pseudomonas aeruginosa and Neisseria gonorrhoeae, at∼ 8 …

Several species of δ proteobacteria are capable of reducing insoluble metal oxides as well
as other extracellular electron acceptors. These bacteria play a critical role in the cycling of …

DNA double strand breaks (DSBs), induced by ionizing radiation (IR) and endogenous
stress including replication failure, are the most cytotoxic form of DNA damage. In human …

Acinetobacter baumannii is a Gram-negative coccobacillus found primarily in hospital
settings that has recently emerged as a source of hospital-acquired infections. A. baumannii …