[PDF][PDF] Enhancement of the Solubility of Poorly Water Soluble Drugs through Solid Dispersion: A Comprehensive Review.

G Singh, L Kaur, GD Gupta… - Indian Journal of …, 2017 - researchgate.net
Solubility is an important determinant in drug liberation and hence drug absorption, which
plays a key role in oral bioavailability of formulations. The dissolution rate of a drug directly …

Advanced formulations for improving therapies with anti-inflammatory or anaesthetic drugs: A review

F Maestrelli, M Bragagni, P Mura - Journal of Drug Delivery Science and …, 2016 - Elsevier
The development of new more effective therapeutic treatments for pain relief is essential for
enhancing the patient quality of life and safety and avoiding or limiting risks of abuse …

Carbon nanotubes buckypapers for potential transdermal drug delivery

A Schwengber, HJ Prado, DA Zilli, PR Bonelli… - Materials Science and …, 2015 - Elsevier
Drug loaded buckypapers based on different types of carbon nanotubes (CNTs) were
prepared and characterized in order to evaluate their potentialities for the design of novel …

Controlled precipitation for enhanced dissolution rate of flurbiprofen: Development of rapidly disintegrating tablets

EA Essa, AO Elmarakby, AMA Donia… - Drug Development …, 2017 - Taylor & Francis
Objective: The aim of this work was to investigate the potential of controlled precipitation of
flurbiprofen on solid surface, in the presence or absence of hydrophilic polymers, as a tool …

Optimizing Nateglinide Liquisolid Compacts: Achieving Formulation Excellence Through the Quality by Design Approach

B Daravath, SK Vemula, N Chella - Journal of Pharmaceutical Innovation, 2024 - Springer
Purpose The present study aimed to improve the dissolution properties of nateglinide, an
anionic drug with poor water solubility and a high log P value, which results in decreased …

Improvement of bioavailability of poorly soluble racecadotril by solid dispersion with surface adsorption method: A case study

B Daravath, GP Kumari - Journal of Reports in Pharmaceutical …, 2021 - journals.lww.com
Materials and Methods: SSDs and physical mixtures (PMs) were prepared using various
ratios of hydrophilic carriers (polyethylene glycol 4000, polyethylene glycol 6000, and …

Development and optimization of Hydrotropic Solid Dispersion of Dexlansoprazole using Central Composite Design approach

R Gulia, S Singh, S Arora… - Journal of Integrated …, 2023 - pubs.thesciencein.org
The objective of current research aims to enhance dissolution of dexlansoprazole (DLP) by
organic solvent free and environment friendly approach through synthesis of hydrotropic …

Surface Solid Dispersion: A Novel Method for improving in-vitro dissolution and in-vivo pharmacokinetics of Meclizine hydrochloride

B Daravath - Research Journal of Pharmacy and Technology, 2021 - indianjournals.com
The current work is aimed to evaluate the role of Gelucire on the solubility; in-vitro
dissolution rate and oral bioavailability of a poorly water soluble drug meclizine …

Enhancement of dissolution rate of racecadotril by liquisolid compact technology

B Daravath, S Somalanka - Brazilian Journal of Pharmaceutical …, 2022 - SciELO Brasil
The current investigation was used to improve the rate of dissolution of an anti-diarrheal
drug ie, racecadotril (RT) at low pH conditions (ie, in the stomach) by reducing the water …

[PDF][PDF] Formulation and Evaluation of Flurbiprofen Solid Dispersions using Novel Carriers for Enhancement of Solubility

A Khan - Asian Journal of Pharmaceutics (AJP), 2020 - asiapharmaceutics.info
Formulation and Evaluation of Flurbiprofen Solid Dispersions using Novel Carriers for
Enhancement of Solubility Page 1 Asian Journal of Pharmaceutics • Jul-Sep 2020 • 14 (3) | 475 …