Comparing early life nutritional sources and human milk feeding practices: personalized and dynamic nutrition supports infant gut microbiome development and …

SR Ames, LC Lotoski, MB Azad - Gut Microbes, 2023 - Taylor & Francis
Exclusive breastfeeding is recommended for the first six months of life, but many infants
receive pumped milk, formula, donor human milk, or other nutritional sources during this …

Multifunctional benefits of prevalent HMOs: Implications for infant health

DR Hill, JM Chow, RH Buck - Nutrients, 2021 - mdpi.com
Breastfeeding is the best source of nutrition during infancy and is associated with a broad
range of health benefits. However, there remains a significant and persistent need for …

TGF-β2 suppresses macrophage cytokine production and mucosal inflammatory responses in the developing intestine

A Maheshwari, DR Kelly, T Nicola, N Ambalavanan… - Gastroenterology, 2011 - Elsevier
BACKGROUND & AIMS: Premature neonates are predisposed to necrotizing enterocolitis
(NEC), an idiopathic, inflammatory bowel necrosis. We investigated whether NEC occurs in …

Pathogenesis of NEC: Role of the innate and adaptive immune response

TL Denning, AM Bhatia, AF Kane, RM Patel… - Seminars in …, 2017 - Elsevier
Necrotizing enterocolitis (NEC) is a devastating disease in premature infants with high case
fatality and significant morbidity among survivors. Immaturity of intestinal host defenses …

Therapeutic potential of gut microbiota and its metabolite short-chain fatty acids in neonatal necrotizing enterocolitis

NA Alsharairi - Life, 2023 - mdpi.com
Short chain fatty acids (SCFAs), the principle end-products produced by the anaerobic gut
microbial fermentation of complex carbohydrates (CHO) in the colon perform beneficial roles …

Is “transfusion‐associated necrotizing enterocolitis” an authentic pathogenic entity?

RD Christensen, DK Lambert, E Henry… - …, 2010 - Wiley Online Library
BACKGROUND: Necrotizing enterocolitis (NEC) sometimes occurs after a transfusion, but it
is unclear whether this is a chance association or cause and effect. STUDY DESIGN AND …

Necrotizing enterocolitis

KM Dominguez, RL Moss - Clinics in perinatology, 2012 - Elsevier
Necrotizing enterocolitis (NEC) is the most common acquired gastrointestinal disease of
premature neonates and is a serious cause of morbidity and mortality. NEC is one of the …

[HTML][HTML] Mapping the new world of necrotizing enterocolitis (NEC): review and opinion

P Gordon, R Christensen, JH Weitkamp… - The e-journal of …, 2012 - ncbi.nlm.nih.gov
A comprehensive review of necrotizing enterocolitis (NEC) is provided; including history,
biological basis and frequently asked questions. In addition, a system of improved NEC …

Paneth cell ablation in the presence of Klebsiella pneumoniae induces necrotizing enterocolitis (NEC)-like injury in the small intestine of immature mice

C Zhang, MP Sherman, LS Prince… - Disease models & …, 2012 - journals.biologists.com
Necrotizing enterocolitis (NEC) is a leading cause of morbidity and mortality in premature
infants. During NEC pathogenesis, bacteria are able to penetrate innate immune defenses …

The development of animal models for the study of necrotizing enterocolitis

C Sodhi, W Richardson, S Gribar… - Disease models & …, 2008 - journals.biologists.com
Necrotizing enterocolitis (NEC) is the leading cause of death and long-term disability from
gastrointestinal disease in preterm infants, and is characterized by acute and chronic …