Substantial advances have been made recently in the pathobiology of pituitary tumors.
Similar to many other endocrine tumors, over the last few years we have recognized the role …

The ability of oestrogens and androgens to stimulate the growth of a number of endocrine
cancers is well established and several endocrine therapies are widely used to reduce the …

X-linked acrogigantism (X-LAG) is a new syndrome of pituitary gigantism, caused by
microduplications on chromosome Xq26. 3, encompassing the gene GPR101, which is …

Accumulating evidence from clinical trials indicates that specific targeting of the IGF1
receptor (IGF1R) is not efficient as an anti-breast cancer treatment. One possible reason is …

Background Pancreatic ductal adenocarcinoma (PDAC) has a poor prognosis, and its
molecular mechanisms are unclear. Nucleolar and spindle-associated protein 1 (NUSAP1) …

Simple Summary Therapy for nonfunctioning pituitary adenomas (NFPAs) is a significant
unmet medical need since these adenomas are frequently invasive, are difficult to resect …

Gonadotroph pituitary adenomas (GPAs) often present as invasive macroadenomas not
amenable to complete surgical resection. Radiotherapy is the only post-operative option for …

Purpose: Novel therapeutic approaches are needed to improve the postoperative
management of residual nonfunctioning pituitary adenomas (NFPA), given their high relapse …

Imaging with 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed
tomography (PET/CT) is used to determine sites of abnormal glucose metabolism to predict …

Background The prognosis of human astrocytoma is poor, and the molecular alterations
underlying its pathogenesis still needed to be elucidated. Nucleolar and spindle associated …