Highlights•We discuss the use of NCRCs for supporting one-carbon assimilation.•
Engineered one-carbon oxidizing enzymes can accept NCRCs.•NCRCs can lower the …

Highlights•Noncanonical redox cofactors (NRCs) can overcome the limitations of natural
cofactors.•NRCs enable specific delivery of reducing power outside of biological …

Despite the increasing demand for efficient and sustainable chemical processes, the
development of scalable systems using biocatalysis for fine chemical production remains a …

Here we demonstrate the preparation of enzyme‐metal biohybrids of NAD+ reductase with
biocatalytically‐synthesised small gold nanoparticles (NPs,< 10 nm) and core‐shell gold …

Ralstonia eutropha H16 is a chemolithoautotrophic bacterium with O2-tolerant hydrogenase
(Hyds) enzymes. Hyds are expressed in the presence of gas mixtures (H2, O2, CO2) or …

Formate dehydrogenases catalyze the reversible oxidation of formate to carbon dioxide.
These enzymes play an important role in CO 2 reduction and serve as nicotinamide cofactor …

Flavin mononucleotide (FMN)‐dependent ene‐reductases constitute a large family of
oxidoreductases that catalyze the enantiospecific reduction of carbon–carbon double bonds …

Enzymatic reductions catalyzed by reductases, such as aldo/ketoreductases (AKRs), imine
reductases, and ene reductases generally depend on the regeneration of nicotinamide …