Review on the computational genome annotation of sequences obtained by next-generation sequencing

GF Ejigu, J Jung - Biology, 2020 - mdpi.com
Simple Summary Due to the development of high-throughput sequencing technologies,
computational genome annotation of sequences has become one of the principal research …

Protein-to-genome alignment with miniprot

H Li - Bioinformatics, 2023 - academic.oup.com
Motivation Protein-to-genome alignment is critical to annotating genes in non-model
organisms. While there are a few tools for this purpose, all of them were developed over 10 …

BRAKER2: automatic eukaryotic genome annotation with GeneMark-EP+ and AUGUSTUS supported by a protein database

T Brůna, KJ Hoff, A Lomsadze, M Stanke… - NAR genomics and …, 2021 - academic.oup.com
The task of eukaryotic genome annotation remains challenging. Only a few genomes could
serve as standards of annotation achieved through a tremendous investment of human …

Improved pea reference genome and pan-genome highlight genomic features and evolutionary characteristics

T Yang, R Liu, Y Luo, S Hu, D Wang, C Wang… - Nature …, 2022 - nature.com
Complete and accurate reference genomes and annotations provide fundamental resources
for functional genomics and crop breeding. Here we report a de novo assembly and …

Long-read sequence assembly: a technical evaluation in barley

M Mascher, T Wicker, J Jenkins, C Plott, T Lux… - The Plant …, 2021 - academic.oup.com
Sequence assembly of large and repeat-rich plant genomes has been challenging,
requiring substantial computational resources and often several complementary sequence …

Shifting the limits in wheat research and breeding using a fully annotated reference genome

International Wheat Genome Sequencing Consortium … - Science, 2018 - science.org
INTRODUCTION Wheat (Triticum aestivum L.) is the most widely cultivated crop on Earth,
contributing about a fifth of the total calories consumed by humans. Consequently, wheat …

Einkorn genomics sheds light on history of the oldest domesticated wheat

HI Ahmed, M Heuberger, A Schoen, DH Koo… - Nature, 2023 - nature.com
Einkorn (Triticum monococcum) was the first domesticated wheat species, and was central
to the birth of agriculture and the Neolithic Revolution in the Fertile Crescent around 10,000 …

Population genomics of the critically endangered kākāpō

N Dussex, T Van Der Valk, HE Morales, CW Wheat… - Cell Genomics, 2021 - cell.com
The kākāpō is a flightless parrot endemic to New Zealand. Once common in the archipelago,
only 201 individuals remain today, most of them descending from an isolated island …

GeneMark-EP+: eukaryotic gene prediction with self-training in the space of genes and proteins

T Brůna, A Lomsadze… - NAR genomics and …, 2020 - academic.oup.com
We have made several steps toward creating a fast and accurate algorithm for gene
prediction in eukaryotic genomes. First, we introduced an automated method for efficient ab …

Repeat-based holocentromeres influence genome architecture and karyotype evolution

PG Hofstatter, G Thangavel, T Lux, P Neumann… - Cell, 2022 - cell.com
The centromere represents a single region in most eukaryotic chromosomes. However,
several plant and animal lineages assemble holocentromeres along the entire chromosome …